ID A0A2K5W0B2_MACFA Unreviewed; 706 AA.
AC A0A2K5W0B2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Solute carrier family 45 member 4 {ECO:0000313|Ensembl:ENSMFAP00000030511.2};
GN Name=SLC45A4 {ECO:0000313|Ensembl:ENSMFAP00000030511.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000030511.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000030511.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000030511.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glycoside-pentoside-hexuronide (GPH) cation
CC symporter transporter (TC 2.A.2) family.
CC {ECO:0000256|ARBA:ARBA00038193}.
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DR RefSeq; XP_015310746.1; XM_015455260.1.
DR AlphaFoldDB; A0A2K5W0B2; -.
DR STRING; 9541.ENSMFAP00000030511; -.
DR Ensembl; ENSMFAT00000004717.2; ENSMFAP00000030511.2; ENSMFAG00000042422.2.
DR VEuPathDB; HostDB:ENSMFAG00000042422; -.
DR GeneTree; ENSGT00950000182914; -.
DR Proteomes; UP000233100; Chromosome 8.
DR Bgee; ENSMFAG00000042422; Expressed in pituitary gland and 13 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR19432:SF7; SOLUTE CARRIER FAMILY 45 MEMBER 4; 1.
DR PANTHER; PTHR19432; SUGAR TRANSPORTER; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 131..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 446..467
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 494..517
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 529..549
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 555..577
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 598..620
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 632..654
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 316..337
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 396..426
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 665..706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 706 AA; 77114 MW; 0D31BBFAA63BD1FA CRC64;
MKMAPQNADP ESMQVQELSV PLPDPQKAGG AEAENCETIS EGSIDRIPVR LWVMHGAVMF
GREFCYAMET ALVTPILLQI GLALGDVPNR QPIGIVLTVL GVVVLDFSAD ATEGPIRAYL
LDVVDSEEQD MALNIHAFSA GLGGAIGYVL GGLDWTQTFL GSWFRTQNQV LFFFAAIIFT
VSVALHLFSI EEEQYSPQQE RSTEEPGALD EGELHSIPAF PDEVQSEHEL ALDYLDVDIV
RSKSDSALHV PDSALDLEPE LLFLHGIEPS IFHDASYPAT PSSTSQELPK TKLPRLVTFL
KEAAKEDETL LDNHLNEAKV PNGSGSPTKD ALGGYSRVDM KPLATSGSVR RRRHAFRRQA
SSTFSYYGKL GSHCYRYRRA NAVVLIKPSR SMSDLYDMQK RQRQRHRHRN QSGATTSSGD
TESEEGEGET TVRLLWLSML KMPRELMRLC LCHLLTWFSV IAEAVFYTDF MGQVIFEGDP
KASSNSTTWQ AYNAGVKMGC WGLVIYAATG AICSALLQKY LDNYDLSVRV IYVLGTLGFS
VGTAVMAMFP NVYVAMVTIS TMGIVSMSIS YCPYALLGQY HDIKQYVHHS PGNSKRGFGI
DCAILSCQVY ISQILVASAL GGVVDAVGTV RVIPMVASVG SFLGFLTATF LVIYPDVSEE
AKEEQKGLSS QLASEGGAGG SSEKPTALKL TRKEGLQGLV ETESVV
//
