ID   A0A2K5W0E4_MACFA        Unreviewed;       455 AA.
AC   A0A2K5W0E4;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   02-JUN-2021, sequence version 2.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=DNA polymerase delta subunit 2 {ECO:0000256|ARBA:ARBA00017588};
GN   Name=POLD2 {ECO:0000313|Ensembl:ENSMFAP00000030549.2};
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000030549.2, ECO:0000313|Proteomes:UP000233100};
RN   [1] {ECO:0000313|Ensembl:ENSMFAP00000030549.2, ECO:0000313|Proteomes:UP000233100}
RP   NUCLEOTIDE SEQUENCE.
RA   Warren W., Wilson R.K.;
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSMFAP00000030549.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the DNA polymerase delta/II small subunit
CC       family. {ECO:0000256|ARBA:ARBA00006035}.
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DR   AlphaFoldDB; A0A2K5W0E4; -.
DR   Ensembl; ENSMFAT00000004755.2; ENSMFAP00000030549.2; ENSMFAG00000042401.2.
DR   VEuPathDB; HostDB:ENSMFAG00000042401; -.
DR   GeneTree; ENSGT00390000006780; -.
DR   Proteomes; UP000233100; Chromosome 3.
DR   Bgee; ENSMFAG00000042401; Expressed in heart and 13 other cell types or tissues.
DR   GO; GO:0043625; C:delta DNA polymerase complex; IEA:UniProt.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   CDD; cd07387; MPP_PolD2_C; 1.
DR   Gene3D; 2.40.50.430; -; 1.
DR   Gene3D; 3.60.21.50; -; 1.
DR   InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR   InterPro; IPR040663; DNA_pol_D_N.
DR   InterPro; IPR024826; DNA_pol_delta/II_ssu.
DR   InterPro; IPR041863; PolD2_C.
DR   PANTHER; PTHR10416; DNA POLYMERASE DELTA SUBUNIT 2; 1.
DR   PANTHER; PTHR10416:SF0; DNA POLYMERASE DELTA SUBUNIT 2; 1.
DR   Pfam; PF18018; DNA_pol_D_N; 1.
DR   Pfam; PF04042; DNA_pol_E_B; 1.
PE   3: Inferred from homology;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233100}.
FT   DOMAIN          49..175
FT                   /note="DNA polymerase delta subunit OB-fold"
FT                   /evidence="ECO:0000259|Pfam:PF18018"
FT   DOMAIN          196..387
FT                   /note="DNA polymerase alpha/delta/epsilon subunit B"
FT                   /evidence="ECO:0000259|Pfam:PF04042"
SQ   SEQUENCE   455 AA;  49602 MW;  19F955245A4B2600 CRC64;
     MFSEQAAQRT HTLLSPPSAN NATFARVPVA TYTNSSQPFR LGERSFSRQY AHIYATRLIQ
     MRPFLENRAQ QHWGSGVGVK KLCELQPEEK CCVVGTLFKA MPLQPSILRE ISEEHNLLPQ
     PPRSKYIHPD DELVLEDELQ RIKLKGTIDV SKLVTGTVLA VFGSVRDDGK FLVEDHCFAD
     LAPQKPAPPL DTDRFVLLVS GLGLGGGGGE SLLGTQLLVD VVTGQLGDEG EQCSAAHVSR
     VILAGNLLSH STQSRDSINK AKYLTKKTQA ASVEAVKMLD EILLQLSASV PVDVMPGEFD
     PTNYTLPQQP LHPCMFPLAT AYSTLQLVTN PYQATIDGVR FLGTSGQNVS DIFRYSSMED
     HLEILEWTLR VRHISPTAPD TLECPHVYFC GNTPSFGSKI IQGPEDQTVL LVTVPDFSAT
     QTACLVNLRS LACQPISFSG FGAEDDDLGG LGLGP
//