ID A0A2K5W282_MACFA Unreviewed; 683 AA.
AC A0A2K5W282;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=ADAMTS like 1 {ECO:0000313|Ensembl:ENSMFAP00000031176.1};
GN Name=ADAMTSL1 {ECO:0000313|Ensembl:ENSMFAP00000031176.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000031176.1, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000031176.1, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000031176.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K5W282; -.
DR Ensembl; ENSMFAT00000005390.2; ENSMFAP00000031176.1; ENSMFAG00000042640.2.
DR VEuPathDB; HostDB:ENSMFAG00000042640; -.
DR GeneTree; ENSGT00940000156243; -.
DR OMA; SGIDSAW; -.
DR Proteomes; UP000233100; Chromosome 15.
DR Bgee; ENSMFAG00000042640; Expressed in adult mammalian kidney and 7 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:InterPro.
DR Gene3D; 2.60.120.830; -; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 6.
DR InterPro; IPR013273; ADAMTS/ADAMTS-like.
DR InterPro; IPR045371; ADAMTS_CR_3.
DR InterPro; IPR010294; ADAMTS_spacer1.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR13723; ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE; 1.
DR PANTHER; PTHR13723:SF157; ADAMTS-LIKE PROTEIN 1; 1.
DR Pfam; PF19236; ADAMTS_CR_3; 1.
DR Pfam; PF05986; ADAMTS_spacer1; 1.
DR Pfam; PF19030; TSP1_ADAMTS; 5.
DR Pfam; PF00090; TSP_1; 1.
DR PRINTS; PR01857; ADAMTSFAMILY.
DR SMART; SM00209; TSP1; 6.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 6.
DR PROSITE; PS50092; TSP1; 6.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW ECO:0000256|PIRSR:PIRSR613273-3};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..683
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014442217"
FT DOMAIN 103..185
FT /note="ADAMTS/ADAMTS-like cysteine-rich"
FT /evidence="ECO:0000259|Pfam:PF19236"
FT DOMAIN 188..296
FT /note="ADAMTS/ADAMTS-like Spacer 1"
FT /evidence="ECO:0000259|Pfam:PF05986"
FT DISULFID 45..76
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 49..81
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 60..66
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
SQ SEQUENCE 683 AA; 75420 MW; 00C586AFFA5D967A CRC64;
MECCRRATPG TLLLFLAFLL LSSRTARSEE DRDGLWDAWG PWSECSRTCG GGASYSLRRC
LSSKSCEGRN IRYRTCSNVD CPPEAGDFRA QQCSAHNDVK HHGQFYEWLP VSNDPDNPCS
LKCQAKGTAL VVELAPKVLD GTRCYTESLD MCISGLCQIV GCDHQLGSTV KEDNCGVCNG
DGSTCRLVRG QYKSQLSATK SDDAVVAIPY GSRHVRLVLK GPDHLYLETK TLQGAKGENS
LSSTGTFLVD NSSVDFQKFP DKEILRMAGP LTADFIVKIR NSGSSDSTVQ FIFYQPIIHR
WRETDFFPCS ATCGGGYQLT SAECYDLRSN RVVADQYCHY YPENIKPKPK LQECNLDPCP
ASDGYKQIMP YDLYHPLPRW EATPWTACSS SCGGGIQSRA VSCVEEDIQG HVTSVEEWKC
MYTPKMPIAQ PCNIFDCPKW LAQEWSPCTV TCGQGLRYRV VLCIDHRGMH TGGCSPKTKP
HIKEECIIPT PCYKPKEKLP VEAKLPWFKQ AQELEEGAAV SEEPSFIPEA WSACTVTCGV
GTQVRIVRCQ VLLSFSQSVA DLPVDECEGP KPASQRACYA GPCSGEIPEF NPDETDGLFG
GLQDFDELYD WEYEGFTKCS ESCGGGVQEA VVSCLNKQTQ EPADENLCVT SRRPPQLLKS
CNLDPCPARS SINSAWKACK VLC
//
