ID A0A2K5W3N5_MACFA Unreviewed; 228 AA.
AC A0A2K5W3N5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Interleukin-33 {ECO:0000256|ARBA:ARBA00016804};
GN Name=IL33 {ECO:0000313|Ensembl:ENSMFAP00000031637.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000031637.1, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000031637.1, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000031637.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle
CC {ECO:0000256|ARBA:ARBA00004398}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}. Secreted
CC {ECO:0000256|ARBA:ARBA00004613}. Vesicle
CC {ECO:0000256|ARBA:ARBA00004373}.
CC -!- SIMILARITY: Belongs to the IL-1 family. Highly divergent.
CC {ECO:0000256|ARBA:ARBA00007933}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_005581826.1; XM_005581769.2.
DR AlphaFoldDB; A0A2K5W3N5; -.
DR Ensembl; ENSMFAT00000005855.2; ENSMFAP00000031637.1; ENSMFAG00000036876.2.
DR VEuPathDB; HostDB:ENSMFAG00000036876; -.
DR GeneTree; ENSGT00390000005185; -.
DR OrthoDB; 4642349at2759; -.
DR Proteomes; UP000233100; Chromosome 15.
DR Bgee; ENSMFAG00000036876; Expressed in lung and 12 other cell types or tissues.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005125; F:cytokine activity; IEA:InterPro.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR026145; IL-33.
DR PANTHER; PTHR21114; DVS27 PROTEIN; 1.
DR PANTHER; PTHR21114:SF0; INTERLEUKIN-33; 1.
DR Pfam; PF15095; IL33; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Transcription {ECO:0000256|ARBA:ARBA00023163}.
SQ SEQUENCE 228 AA; 25706 MW; 160CBE300DD9DE03 CRC64;
MKPKMKYSTN KISTAKRKNT ASKALCFKLG KSQQKAKEVC HVYFMKLRSG LMIKKEACYF
RRETTKRPSL KTGGKHKGHL VLAACQQQST VECFAFGISG VPKYTRALHD SSITDKVLLS
YYESQHPSSE SGDGVDGKML MVTLSPTKDF WLQANNKEHS VELHKCEKPL PDQAFFVLHN
RSFNCVSFEC KTDPGVFIGV KDNHLALIKV DYSENLGSEN ILFKLSEI
//
