ID   A0A2K5W743_MACFA        Unreviewed;       115 AA.
AC   A0A2K5W743;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Interleukin-7 {ECO:0000256|ARBA:ARBA00019460};
GN   Name=IL7 {ECO:0000313|Ensembl:ENSMFAP00000032906.1};
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000032906.1, ECO:0000313|Proteomes:UP000233100};
RN   [1] {ECO:0000313|Ensembl:ENSMFAP00000032906.1, ECO:0000313|Proteomes:UP000233100}
RP   NUCLEOTIDE SEQUENCE.
RA   Warren W., Wilson R.K.;
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSMFAP00000032906.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the IL-7/IL-9 family.
CC       {ECO:0000256|ARBA:ARBA00007621}.
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DR   AlphaFoldDB; A0A2K5W743; -.
DR   Ensembl; ENSMFAT00000007130.2; ENSMFAP00000032906.1; ENSMFAG00000002965.2.
DR   VEuPathDB; HostDB:ENSMFAG00000002965; -.
DR   GeneTree; ENSGT00390000004451; -.
DR   Proteomes; UP000233100; Chromosome 8.
DR   Bgee; ENSMFAG00000002965; Expressed in liver and 7 other cell types or tissues.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0008083; F:growth factor activity; IEA:InterPro.
DR   GO; GO:0005139; F:interleukin-7 receptor binding; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   Gene3D; 1.20.1250.50; -; 2.
DR   InterPro; IPR001181; IL-7.
DR   InterPro; IPR038325; IL7_sf.
DR   PANTHER; PTHR48404; INTERLEUKIN-7; 1.
DR   PANTHER; PTHR48404:SF1; INTERLEUKIN-7; 1.
DR   Pfam; PF01415; IL7; 1.
DR   PRINTS; PR00435; INTERLEUKIN7.
DR   SMART; SM00127; IL7; 1.
PE   3: Inferred from homology;
KW   Cytokine {ECO:0000256|ARBA:ARBA00022514};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Growth factor {ECO:0000256|ARBA:ARBA00023030};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           26..115
FT                   /note="Interleukin-7"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5014341133"
SQ   SEQUENCE   115 AA;  13387 MW;  581F06E3FEEA6F32 CRC64;
     MFHVSFRYIF GLPPLILVLL PVASSDCDIE GKDGKQYESV LMVSIDQLLD SMKEIGSNCL
     NNEFNFFKRH LCDDNKEENK SLKEQKKLND SCFLKRLLQK IKTCWNKILM GTKEH
//