ID A0A2K5W928_MACFA Unreviewed; 275 AA.
AC A0A2K5W928;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=RAB33B, member RAS oncogene family {ECO:0000313|Ensembl:ENSMFAP00000033601.2};
GN Name=RAB33B {ECO:0000313|Ensembl:ENSMFAP00000033601.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000033601.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000033601.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000033601.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC {ECO:0000256|ARBA:ARBA00006270}.
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DR AlphaFoldDB; A0A2K5W928; -.
DR STRING; 9541.ENSMFAP00000033601; -.
DR Ensembl; ENSMFAT00000007829.2; ENSMFAP00000033601.2; ENSMFAG00000003290.2.
DR VEuPathDB; HostDB:ENSMFAG00000003290; -.
DR GeneTree; ENSGT00940000157090; -.
DR OrthoDB; 8685at2759; -.
DR Proteomes; UP000233100; Chromosome 5.
DR Bgee; ENSMFAG00000003290; Expressed in liver and 13 other cell types or tissues.
DR GO; GO:0005796; C:Golgi lumen; IEA:Ensembl.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:Ensembl.
DR GO; GO:0000045; P:autophagosome assembly; IEA:Ensembl.
DR GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IEA:Ensembl.
DR GO; GO:1903434; P:negative regulation of constitutive secretory pathway; IEA:Ensembl.
DR GO; GO:0034067; P:protein localization to Golgi apparatus; IEA:Ensembl.
DR GO; GO:0032482; P:Rab protein signal transduction; IEA:InterPro.
DR GO; GO:1903358; P:regulation of Golgi organization; IEA:Ensembl.
DR GO; GO:2000156; P:regulation of retrograde vesicle-mediated transport, Golgi to ER; IEA:Ensembl.
DR GO; GO:0048705; P:skeletal system morphogenesis; IEA:Ensembl.
DR CDD; cd04115; Rab33B_Rab33A; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041822; Rab33A/B.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR47978; -; 1.
DR PANTHER; PTHR47978:SF66; RAS-RELATED PROTEIN RAB-33B; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00176; RAN; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51417; ARF; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
PE 3: Inferred from homology;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100}.
SQ SEQUENCE 275 AA; 30473 MW; 462ACAE8BEDD2224 CRC64;
MPHPQRQAEG TCLFSGATKR YIGAGTDLTP EATSLPSLSS LGRLGGMAEE MESSLEASFS
SSGAVSGASG FLPPARSRIF KIIVIGDSNV GKTCLTYRFC AGRFPDRTEA TIGVDFRERA
VEIDGERIKI QLWDTAGQER FRKSMVQHYY RNVHAVVFVY DMTNMASFHS LPSWIEECKQ
HLLANDIPRI LVGNKCDLRS AIQVPTDLAQ KFADTHSMPL FETSAKNPND NDHVEAIFMT
LAHKLKSHKP LMLSQPPDNE IILKPEPKPA TTCWC
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