ID A0A2K5WFL1_MACFA Unreviewed; 752 AA.
AC A0A2K5WFL1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Heterogeneous nuclear ribonucleoprotein U like 1 {ECO:0000313|Ensembl:ENSMFAP00000035902.2};
GN Name=HNRNPUL1 {ECO:0000313|Ensembl:ENSMFAP00000035902.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000035902.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000035902.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000035902.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A2K5WFL1; -.
DR Ensembl; ENSMFAT00000010143.2; ENSMFAP00000035902.2; ENSMFAG00000034257.2.
DR VEuPathDB; HostDB:ENSMFAG00000034257; -.
DR GeneTree; ENSGT00940000157823; -.
DR Proteomes; UP000233100; Chromosome 19.
DR Bgee; ENSMFAG00000034257; Expressed in thymus and 13 other cell types or tissues.
DR CDD; cd12884; SPRY_hnRNP; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR035778; SPRY_hnRNP_U.
DR PANTHER; PTHR12381; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER; 1.
DR PANTHER; PTHR12381:SF41; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U-LIKE PROTEIN 1; 1.
DR Pfam; PF13671; AAA_33; 1.
DR Pfam; PF02037; SAP; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS50800; SAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233100}.
FT DOMAIN 3..37
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT REGION 32..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 103..162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 481..707
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..156
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..500
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 549..579
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 580..607
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..666
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 667..681
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 690..704
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 752 AA; 84474 MW; 2418BC57F2B3471A CRC64;
MDVRRLKVNE LREELQRRGL DTRGLKAELA ERLQPPPPGL QPHAEPGGYS GPDGHYAMDN
ITRQNQFYDT QVIKQENESG YERRPLEMEQ QQVYRPEMKT EMKQGAPTGF LPPEASQLKP
DRQQFQSRKR PYEENRGRGY FEHREDRRGR SPQPPAEEDE DDFDDTLVAI DTYNCDLHFK
VARDRSSGYP LTIEGFAYLW SGARASYGVR RGRVCFEMKD FECGNDVELS FTKNGKWMGI
AFRIQKEALG GQALYPHVLV KNCAVEFNFG QRAEPYCSVL PGFTFIQHLP LSERIRGTVG
PKSKAECEIL MMVGLPAAGK TTWAIKHAAS NPSKKYNILG TNAIMDKMRV MGLRRQRNYA
GRWDVLIQQA TQCLNRLIQI AARKKRNYIL DQTNVYGSAQ RRKMRPFEGF QRKAIVICPT
DEDLKDRTIK RTDEEGKDVP DHAVLEMKAN FTLPDVGDFL DEVLFIELQR EEADKLVRQY
NEEGRKAGPP PEKRFDNRGG GGFRGRGGGG GFQRYDNRGP PGGNRGGFQN RGGGSGGGGN
YRGGFNRSGG GGYSQNRWGN NNRDNNNSNN RGSYNRAPQQ QPPPQQPPPP QPPPQQPPPP
PSYSPARNPP GASTYNKNSN IPGSSANTST PTVSSYSPPQ SFGFFPSTFQ PSYSQSPYNQ
GGYSQGYTAP PPPPPPPPAY NYGSYGGYNP APYTPPPPPT AQTYPQPSYN QYQQYAQQWN
QYYQNQGQWP PYYGNYDYGS YSGNTQGGTS TQ
//
