ID A0A2K5WJ07_MACFA Unreviewed; 536 AA.
AC A0A2K5WJ07;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Prickle planar cell polarity protein 3 {ECO:0000313|Ensembl:ENSMFAP00000037036.2};
GN Name=PRICKLE3 {ECO:0000313|Ensembl:ENSMFAP00000037036.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000037036.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000037036.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000037036.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the prickle / espinas / testin family.
CC {ECO:0000256|ARBA:ARBA00008268}.
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DR AlphaFoldDB; A0A2K5WJ07; -.
DR STRING; 9541.ENSMFAP00000037036; -.
DR Ensembl; ENSMFAT00000011286.2; ENSMFAP00000037036.2; ENSMFAG00000037781.2.
DR VEuPathDB; HostDB:ENSMFAG00000037781; -.
DR GeneTree; ENSGT00940000153629; -.
DR OrthoDB; 370973at2759; -.
DR Proteomes; UP000233100; Chromosome X.
DR Bgee; ENSMFAG00000037781; Expressed in skeletal muscle tissue.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd09415; LIM1_Prickle; 1.
DR CDD; cd09418; LIM2_Prickle; 1.
DR CDD; cd09420; LIM3_Prickle; 1.
DR CDD; cd09827; PET_Prickle; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 3.
DR InterPro; IPR033725; LIM1_prickle.
DR InterPro; IPR033726; LIM2_prickle.
DR InterPro; IPR033727; LIM3_prickle.
DR InterPro; IPR010442; PET_domain.
DR InterPro; IPR033723; PET_prickle.
DR InterPro; IPR047120; Pk/Esn/Tes.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24211; LIM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24211:SF19; PRICKLE PLANAR CELL POLARITY PROTEIN 3; 1.
DR Pfam; PF00412; LIM; 3.
DR Pfam; PF06297; PET; 1.
DR SMART; SM00132; LIM; 3.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 2.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 2.
DR PROSITE; PS51303; PET; 1.
PE 3: Inferred from homology;
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 6..114
FT /note="PET"
FT /evidence="ECO:0000259|PROSITE:PS51303"
FT DOMAIN 116..180
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 181..241
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 329..536
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 329..348
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..419
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..448
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 455..477
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 500..514
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 536 AA; 59198 MW; 9BB78EA18EF816CC CRC64;
MCRLISDFQR HSISDDDSGC ASEEYAWVPP GLKPEQVYQF FSCLPEDKVP YVNSPGEKYR
IKQLLHQLPP HDSEAQYCTA LEEEEKKELR AFSQQRKREN LGRGIVRIFP VTITGAICEE
CGKQIGGGDI AVFASRAGLG ACWHPQCFVC TTCRELLVDL IYFYHAGKVY CGRHHAECLR
PRCQACDEII FSPECTEAEG RHWHMDHFCC FECEASLGGQ RYVMRQSRPH CCACYEARHA
EYCDGCGEHI GLDQGQMAYE GQHWHASDRC FCCSRCGRAL LGRPFLPRRG LIFCSRACSL
GSEPTAPGPG RRSWSAGTVT APLAASTASF SAAEGASETT TKGTCTESAP ATGPEEPSRF
RPTATPCRSW GSAVPPSPQS PPGQPNLAPH VSFRDPLVFE GGPPDPECTP GPAPQATQSP
PRAPSRHRHR HNHHHHHHHH HRHPSRRRHY QCDAGSGSDS GSCSSSPSSS SSESSEDDGF
FLGERIPLPP HLCRPMPAQD NATETFNSPS LSLPRDSRPG MPRQTRQTRD KNCIVA
//
