ID A0A2K5WMN9_MACFA Unreviewed; 326 AA.
AC A0A2K5WMN9;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=14-3-3 protein gamma {ECO:0000256|ARBA:ARBA00039672};
GN Name=YWHAG {ECO:0000313|Ensembl:ENSMFAP00000038430.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000038430.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000038430.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000038430.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the 14-3-3 family.
CC {ECO:0000256|ARBA:ARBA00006141, ECO:0000256|RuleBase:RU003466}.
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DR AlphaFoldDB; A0A2K5WMN9; -.
DR STRING; 9541.ENSMFAP00000038430; -.
DR Ensembl; ENSMFAT00000012685.2; ENSMFAP00000038430.2; ENSMFAG00000038574.2.
DR VEuPathDB; HostDB:ENSMFAG00000038574; -.
DR GeneTree; ENSGT01090000260061; -.
DR OrthoDB; 920089at2759; -.
DR Proteomes; UP000233100; Chromosome 3.
DR Bgee; ENSMFAG00000038574; Expressed in temporal lobe and 13 other cell types or tissues.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0005159; F:insulin-like growth factor receptor binding; IEA:Ensembl.
DR GO; GO:0050815; F:phosphoserine residue binding; IEA:Ensembl.
DR GO; GO:0019904; F:protein domain specific binding; IEA:Ensembl.
DR GO; GO:0005080; F:protein kinase C binding; IEA:Ensembl.
DR GO; GO:0140311; F:protein sequestering activity; IEA:Ensembl.
DR GO; GO:0042149; P:cellular response to glucose starvation; IEA:Ensembl.
DR GO; GO:1904262; P:negative regulation of TORC1 signaling; IEA:Ensembl.
DR GO; GO:0006605; P:protein targeting; IEA:Ensembl.
DR GO; GO:0045664; P:regulation of neuron differentiation; IEA:Ensembl.
DR GO; GO:0048167; P:regulation of synaptic plasticity; IEA:Ensembl.
DR CDD; cd10024; 14-3-3_gamma; 1.
DR Gene3D; 1.20.190.20; 14-3-3 domain; 1.
DR InterPro; IPR000308; 14-3-3.
DR InterPro; IPR023409; 14-3-3_CS.
DR InterPro; IPR036815; 14-3-3_dom_sf.
DR InterPro; IPR023410; 14-3-3_domain.
DR PANTHER; PTHR18860; 14-3-3 PROTEIN; 1.
DR PANTHER; PTHR18860:SF22; 14-3-3 PROTEIN GAMMA; 1.
DR Pfam; PF00244; 14-3-3; 1.
DR PRINTS; PR00305; 1433ZETA.
DR SMART; SM00101; 14_3_3; 1.
DR SUPFAM; SSF48445; 14-3-3 protein; 1.
DR PROSITE; PS00796; 1433_1; 1.
DR PROSITE; PS00797; 1433_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000233100}.
FT DOMAIN 83..326
FT /note="14-3-3"
FT /evidence="ECO:0000259|SMART:SM00101"
FT REGION 1..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 58..75
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 326 AA; 36616 MW; C0BEA087C0BAE0DF CRC64;
MRRGRGRRGC PSVARTAAAA ASLPVPRSQL QPPPPRSRRL SRSLRGSVLS GTWAPIAPSK
PFTPPQCPPP SPARPSSAKM VDREQLVQKA RLAEQAERYD DMAAAMKNVT ELNEPLSNEE
RNLLSVAYKN VVGARRSSWR VISSIEQKTS ADGNEKKIEM VRAYREKIEK ELEAVCQDVL
SLLDNYLIKN CSETQYESKV FYLKMKGDYY RYLAEVATGE KRATVVESSE KAYSEAHEIS
KEHMQPTHPI RLGLALNYSV FYYEIQNAPE QACHLAKTAF DDAIAELDTL NEDSYKDSTL
IMQLLRDNLT LWTSDQQDDD GGEGNN
//
