ID A0A2K5WQH1_MACFA Unreviewed; 607 AA.
AC A0A2K5WQH1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Activating transcription factor 6 {ECO:0000313|Ensembl:ENSMFAP00000039425.2};
GN Name=ATF6 {ECO:0000313|Ensembl:ENSMFAP00000039425.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000039425.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000039425.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000039425.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the bZIP family. ATF subfamily.
CC {ECO:0000256|ARBA:ARBA00009050}.
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DR AlphaFoldDB; A0A2K5WQH1; -.
DR STRING; 9541.ENSMFAP00000039425; -.
DR Ensembl; ENSMFAT00000013688.2; ENSMFAP00000039425.2; ENSMFAG00000059314.1.
DR VEuPathDB; HostDB:ENSMFAG00000045916; -.
DR GeneTree; ENSGT00940000159221; -.
DR OrthoDB; 5396881at2759; -.
DR Proteomes; UP000233100; Chromosome 1.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd14700; bZIP_ATF6; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR PANTHER; PTHR46164; ATF6, ISOFORM C; 1.
DR PANTHER; PTHR46164:SF1; CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-6 ALPHA; 1.
DR Pfam; PF00170; bZIP_1; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; Leucine zipper domain; 1.
DR PROSITE; PS50217; BZIP; 1.
DR PROSITE; PS00036; BZIP_BASIC; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100}.
FT DOMAIN 306..369
FT /note="BZIP"
FT /evidence="ECO:0000259|PROSITE:PS50217"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 90..183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 331..365
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 92..146
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..179
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 607 AA; 67288 MW; 64468FD7DF8CC4D1 CRC64;
MGESGGVAGT MESPFSPGLS HRLDEDWDSG LFAELGYFTD TDELQLEAAN ETYENNFDHL
DFDLDLMPWE SDIWDINNQI CTVKDIKAEP QPLSPASSSY SVSSPQSVDS YSSTQHVPEE
LDLSSSSQMS PLSLYGESSN SPSSAEPLKE DKPVTGPRNK TENGLTPKKK IQVNSKPSIQ
PKPLLLPAAP KTQTNSSVPA KTIIIQTVPT LMPLAKQPPI ISLQPAPTKG QTVLLSQPTV
VQLQAPGVLP SAQPVLAVAG GVTQLPNHVV NVVPAPSANS PVNGKLSVTK PVLQSTMRNV
GSDIAVLRRQ QRMIKNRESA CQSRKKKKEY MLGLEARLKA ALSENEQLKK ENGTLKRQLD
EVVSENQRLK VPSPKRRAVC VMIVLAFIIL NYGPMSMLEQ DSRRMNPSVS PANQRRHLLG
FSAKEAQDTS DGVIQKNSYR YDHSVSNDKA LMVLTEEPLL YIPPPPCQPL INTTESLRLN
HELRGWVHRH EVERTKSRRM TNNQQKTRIL QGALEQGSNS QLMAVQYTET TSISRNSGSE
LQVYYASPRS YQDFFEAIRR RGDTFYVVSF RRDHLLLPAT THNKTTRPKM SIVLPAININ
ELEKLAS
//
