ID A0A2K5WWD0_MACFA Unreviewed; 675 AA.
AC A0A2K5WWD0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Upstream binding transcription factor {ECO:0000313|Ensembl:ENSMFAP00000041519.2};
GN Name=UBTF {ECO:0000313|Ensembl:ENSMFAP00000041519.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000041519.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000041519.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000041519.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K5WWD0; -.
DR Ensembl; ENSMFAT00000015795.2; ENSMFAP00000041519.2; ENSMFAG00000041241.2.
DR VEuPathDB; HostDB:ENSMFAG00000041241; -.
DR GeneTree; ENSGT00940000161141; -.
DR OrthoDB; 4260911at2759; -.
DR Proteomes; UP000233100; Chromosome 16.
DR Bgee; ENSMFAG00000041241; Expressed in lymph node and 13 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd21998; HMG-box_UBF1_rpt1-like; 1.
DR CDD; cd22000; HMG-box_UBF1_rpt3; 1.
DR CDD; cd22002; HMG-box_UBF1_rpt5; 1.
DR CDD; cd22003; HMG-box_UBF1_rpt6-like; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 4.
DR InterPro; IPR029215; HMG_box_5.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR46318:SF4; NUCLEOLAR TRANSCRIPTION FACTOR 1; 1.
DR PANTHER; PTHR46318; UPSTREAM BINDING TRANSCRIPTION FACTOR; 1.
DR Pfam; PF00505; HMG_box; 1.
DR Pfam; PF09011; HMG_box_2; 1.
DR Pfam; PF14887; HMG_box_5; 1.
DR SMART; SM00398; HMG; 4.
DR SUPFAM; SSF47095; HMG-box; 4.
DR PROSITE; PS50118; HMG_BOX_2; 4.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 112..180
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 261..325
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 393..460
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 479..545
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 112..180
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 261..325
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 393..460
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 479..545
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 343..398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 457..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 559..675
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 361..398
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 567..582
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 587..657
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 658..675
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 675 AA; 78778 MW; 5DC3C86F22865605 CRC64;
MNGEADCPTD LEMAAPKGQD RWSQEDMLTL LECMKNNLPS NDSSKFKTTE SHMDWEKVAF
KDFSGDMCKL KWVEISNEVR KFRTLTELIL DAQEHVKNPY KGKKLKKHPD FPKKPLTPYF
RFFMEKRAKY AKLHPEMSNL DLTKILSKKY KELPEKKKMK YIQDFQREKQ EFERNLARFR
EDHPDLIQNA KKSDIPEKPK TPQQLWYTHE KKVYLKVRPD EIMRDYIQKH PELNISEEGI
TKSTLTKAER QLKDKFDGRP TKPPPNSYSL YCAELMANMK DVPSTERMVL CSQQWKLLSQ
KEKDAYHKKC DQKKKDYEVE LLRFLESLPE EEQQRVLGEE KMLNINKKQA TSPASKKPAQ
EGGKAKYKAR EAALKAQSER KPGGEREERG KLPESPKRAE EIWQQSVIGD YLARFKNDRV
KALKAMEMTW NNMEKKEKLM WIKKAAEDQK RYERELSEMR APPAATNSSK KMKFQGEPKK
PPMNGYQKFS QELLSNGELN HLPLKERMVE IGSRWQRISQ SQKEHYKKLA EEQQKQYKVH
LDLWVKSLSP QDRAAYKEYI SNKRKSMTKL RGPNPKSSRT TLQSKSESEE DDEEDEDDED
EDEEEEDDEN GDSSEDGGDS SESSSEDESE DGDENEEDDE DEDDDEDDDE DEDNESEGSS
SSSSSSGDSS DSDSN
//
