ID   A0A2K5WWJ3_MACFA        Unreviewed;       619 AA.
AC   A0A2K5WWJ3;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   02-JUN-2021, sequence version 2.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=Amino acid transporter {ECO:0000256|RuleBase:RU361216};
GN   Name=SLC1A7 {ECO:0000313|Ensembl:ENSMFAP00000041399.2};
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000041399.2, ECO:0000313|Proteomes:UP000233100};
RN   [1] {ECO:0000313|Ensembl:ENSMFAP00000041399.2, ECO:0000313|Proteomes:UP000233100}
RP   NUCLEOTIDE SEQUENCE.
RA   Warren W., Wilson R.K.;
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSMFAP00000041399.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU361216}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361216}.
CC   -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC       (DAACS) (TC 2.A.23) family. {ECO:0000256|RuleBase:RU361216}.
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DR   AlphaFoldDB; A0A2K5WWJ3; -.
DR   STRING; 9541.ENSMFAP00000041399; -.
DR   Ensembl; ENSMFAT00000015675.2; ENSMFAP00000041399.2; ENSMFAG00000041399.2.
DR   VEuPathDB; HostDB:ENSMFAG00000041399; -.
DR   GeneTree; ENSGT00940000156073; -.
DR   Proteomes; UP000233100; Chromosome 1.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015501; F:glutamate:sodium symporter activity; IEA:Ensembl.
DR   GO; GO:0015179; F:L-amino acid transmembrane transporter activity; IEA:UniProt.
DR   GO; GO:0001504; P:neurotransmitter uptake; IEA:Ensembl.
DR   Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR   InterPro; IPR001991; Na-dicarboxylate_symporter.
DR   InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR   InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR   PANTHER; PTHR11958:SF22; EXCITATORY AMINO ACID TRANSPORTER 5; 1.
DR   PANTHER; PTHR11958; SODIUM/DICARBOXYLATE SYMPORTER-RELATED; 1.
DR   Pfam; PF00375; SDF; 2.
DR   PRINTS; PR00173; EDTRNSPORT.
DR   SUPFAM; SSF118215; Proton glutamate symport protein; 2.
DR   PROSITE; PS00713; NA_DICARBOXYL_SYMP_1; 1.
DR   PROSITE; PS00714; NA_DICARBOXYL_SYMP_2; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361216};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW   Symport {ECO:0000256|ARBA:ARBA00022847, ECO:0000256|RuleBase:RU361216};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU361216};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU361216};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361216}.
FT   TRANSMEM        20..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        60..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        95..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        220..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        260..281
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        293..319
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        325..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
SQ   SEQUENCE   619 AA;  67025 MW;  E4A95FA30796AA67 CRC64;
     MVLHAILARG RDVCRRNGLL ILSVLSVIVG CLLGFFLRTR HLSPQEISYF QFPGELLMRM
     LKMMILPLVV SSLMSGLASL DAKTSSRLGV LTVAYYLWTT FMAVIVGIFM VSIIHPGGAA
     QKETTEQSGK PIMSSADALL DLIRNMFPAN LVEATFKQYR TKTTPVVKSP KVAPEEAPPR
     RILIYGVQEE NGSRVQNFAL DLTPPPEVIY KSEPGTSDGM NVLGIVFFSA TMGIMLGRMG
     ESGAPLVSFC QCLNESVMKI VAVAVWYFPF GIVFLIAGKI LEMDDPRAVG KKLGFYSVTV
     VCGLVLHGLF ILPLLYFFIT KKNPIVFIRG ILQALLIALA TSSRKNQVRA LQCPRSFPPA
     AAAPQEHKHS WWGGCLGWGE LPNGGPGHPG RGCWADTGPS NRSSATLPIT FKCLLENNHI
     DRRIARFVLP VGATINMDGT ALYEAVAAIF IAQVNNYELD FGQIITISIT ATAASIGAAG
     IPQAGLVTMV IVLTSVGLPT DDITLIIAVD WALDRFRTMI NVLGDALAAG IMAHICRKDF
     ARDTGTEKLL PCETKPVSLQ EIVAAQQNGC VKSVAEASEL TLGPTCPHHI PVQVEQDEEP
     PAVSLDHCTI QISELETNV
//