ID A0A2K5WYF7_MACFA Unreviewed; 272 AA.
AC A0A2K5WYF7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Guanylate kinase 1 {ECO:0000313|Ensembl:ENSMFAP00000042252.2};
GN Name=GUK1 {ECO:0000313|Ensembl:ENSMFAP00000042252.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000042252.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000042252.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000042252.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the guanylate kinase family.
CC {ECO:0000256|ARBA:ARBA00005790}.
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DR AlphaFoldDB; A0A2K5WYF7; -.
DR STRING; 9541.ENSMFAP00000042252; -.
DR Ensembl; ENSMFAT00000016533.2; ENSMFAP00000042252.2; ENSMFAG00000039838.2.
DR VEuPathDB; HostDB:ENSMFAG00000039838; -.
DR GeneTree; ENSGT00940000155815; -.
DR Proteomes; UP000233100; Chromosome 1.
DR Bgee; ENSMFAG00000039838; Expressed in temporal lobe and 13 other cell types or tissues.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.63.10; Guanylate Kinase phosphate binding domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23117:SF13; GUANYLATE KINASE; 1.
DR PANTHER; PTHR23117; GUANYLATE KINASE-RELATED; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR SMART; SM00072; GuKc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 111..263
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 272 AA; 30542 MW; 7076CC891EDD0010 CRC64;
MVGSRKEEIL PPEQEVPFQE SGCWGSMGAQ SRERSGRDHS GTWICAGGSQ ETFHLGAPVE
TTCLAASSLT PRHVRPQACG AEWAFGSWEE HPAEEAAPGA QRHLWLQRVP YHKEPEAWRG
EWQREVMQRD IAAGDFIEHA EFSGNLYGTS KAAVQAVQAM NRICVLDVDL QGVRNIKATD
LRPIYISVQP PSLHVLEQRL RQRNTETEES LAKRLAAARA DMESRNQESS KDRRLRLALC
SRHPRPIQDQ GSSTEPPPWQ VIRQLCALGQ HM
//
