ID A0A2K5X769_MACFA Unreviewed; 2498 AA.
AC A0A2K5X769;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Jumonji domain containing 1C {ECO:0000313|Ensembl:ENSMFAP00000045323.2};
GN Name=JMJD1C {ECO:0000313|Ensembl:ENSMFAP00000045323.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000045323.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000045323.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000045323.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR Ensembl; ENSMFAT00000019627.2; ENSMFAP00000045323.2; ENSMFAG00000000341.2.
DR VEuPathDB; HostDB:ENSMFAG00000000341; -.
DR GeneTree; ENSGT00940000158210; -.
DR Proteomes; UP000233100; Chromosome 9.
DR Bgee; ENSMFAG00000000341; Expressed in cerebellum and 13 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0032454; F:histone H3K9 demethylase activity; IEA:InterPro.
DR Gene3D; 2.60.120.650; Cupin; 1.
DR InterPro; IPR045109; JHDM2-like.
DR InterPro; IPR003347; JmjC_dom.
DR PANTHER; PTHR12549; JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN; 1.
DR PANTHER; PTHR12549:SF6; JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 2C-RELATED; 1.
DR Pfam; PF02373; JmjC; 1.
DR SMART; SM00558; JmjC; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51184; JMJC; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233100}.
FT DOMAIN 2232..2456
FT /note="JmjC"
FT /evidence="ECO:0000259|PROSITE:PS51184"
FT REGION 235..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 590..616
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1202..1222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1572..1650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1929..2022
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 235..269
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..415
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 416..440
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1572..1641
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1929..1963
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1973..2004
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2005..2022
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2498 AA; 279804 MW; FC1F2877FA4DA7BD CRC64;
MAVETRPELV GKRFLCVAVS DEARPERWES GRGWRAGVIR AVSHRDSRNP DLAVYVEFDD
LEWDKREWVK VYEDFSTFLV EYHLIWAKRN DPSQTQGSKS KQIQWPALDD IDSLNPVLRD
NPQLHEEVKV WVKEQKVQEI FMQGPYSLNG YRVRVYRQDS ATQWFTGIIT HHDLFTRTMI
VMNDQVLEPQ NVDPSMVQMT FLDDVVHSLL KGENIGITSR RRSRANHNVN TVHSHYTRAQ
ANSPRPAMNS QAAVPKQNMH QQQQQRSIRP NKRKGSDSSI PDEEKMKEEK YDYISRGENP
KGKNKHLMNK RRKPEEDEKK LNMKRLRTDN VSDFSESSDS ENSNKRIIDN SSEQKSENEL
KNKNTSKING EEGKPHNNEK AGEETLKDSQ PPWDQIQEDK KHEEAEKRKS VDTQLQEDMI
IHSSEQSTVS DHNSNDLLPQ ECSMEKTHTM ELLPKEKFVS RPPTPKCVID ITNDTNLEKV
AQENSSTFGL QTLQKMDPNV SDSKHSIANA KFLETAKQDS DQSWVSDVVK VDLTQSSVTN
ASSGNDHLNM EKEKYVSYIS PLSAVSVMED KLHKRSPPPE TIKSKLNTSV DTHKIKSSPS
PEVVKPKITH SPDSVKSKAT YVNSQATGER RLANKIEHEL SRCSFHPIPT RSSTLENTKS
PLIIDKNEHF TVYRDPALIG SETGANHISP FLSQHPFPLH SSSHRTCLNP GTHHPALTPA
PHLLAGSSSQ TPLPTINTHP LTSGPHHAVH HPHLLPTVLP GVPTASLLGG HPRLESAHAS
SLSHLALAHQ QQQQLLQHQS PHLLGQAHPS ASYNQLGLYP IIWQYPNGTH AYSGLGLPSS
KWIHPENAVN AEASLRRNSP SPWLHQPTPV TSADGIGLLS HIPVRPSSAE PHRPLKITAH
SSPPLTKTLV DHHKEELERK AFMEPLRSVA STSAKNDLDL NRSQTGKDCH LHRHFVDPVL
NQLQRPPQET GERLNKYKEE HRRILQESID VAPFTTKIKG LEGERENYSR VASSSSSPKS
HAIKQDMDVE RSVSDLYKMK HSVPQSLPQS NYFTTLSNSV VNEPPRSYPS KEISNIYGDK
QSNALAAAAA NPQTLTSFIT SLSKPPPLIK HQPESEGLVG KIPEHLPHQI ASHSVTAFRN
DCRSPTHLTI SSTNTLRSMP ALHRAPVFHP PIHHSLERKE GSYSSLSPPT LTPVMPVNAG
GKIQESQKPP TLIPEPKDSQ ANFKSSSEQS LTEMWRPNNN FSKEKTEWHV EKSSGKLQAA
MASVIVRPSS STKTDSMPAV QLASKDQVSE RSSAGAHKTD CLKLAEAGET GRIILPNVNS
DSVHTKSEKN FQAVSQGSVP SSVMSVNTMC NTKTDVITSA ADTTSVSSWG GSEAISSLSN
TILASTSSEC TSSKSVSQPV AQKQECKVST TAPVTLASSK TGSVVQPSSG FSGTTDFIHL
KKHKAALAAA QYKSSNVSET EPNAIKSQTL SASLPLDSTV ICSTINKANS VGNGQASQTS
QPNYHTKLKK AWLTRHSEED KNTNKMENSG NSVSEIIKPC SVNLIASTSS DIQNSVDSKI
IVDKYVKDDK VNRRKAKRTY ESGSESGDSD ESESKSEQRT KRQPKPTYKK KQNDLQKRKG
EIEEDLKPNG VLSRSAKEKS KLKLQSNSNT GIPRSVLKDW RKVKKLKQTG ESFLQDDSCC
EIGPNLQKCR ECRLIRSKKG EEPAHSPVFC RFYYFRRLSF SKNGVVRIDG FSSPDQYDDE
AMSLWTHENY EDDELDIETS KYILDIIGDK FCQLVTSEKT ALSWVKKDAK IAWKRAVRGV
REMCDACEAT LFNIHWVCQK CGFVVCLDCY KAKERKSSRD KELYAWMKCV KGQPHDHKHL
MPTQIIPGSV LTDLLDAMHT LREKYGIKSH CHCTNKQNLQ VGNFPTMNGV SQVLQNVLNH
SNKISLCMPE SQQQNTPQKS EKNGGSSPES DVGTDNKLTP PESQSPLHWL ADLAEQKARE
EKKENKELTL EKQIKEEREQ DNSESPNGRT SPLVSQNNEQ GSTLRDLLTT TAGKLRVGST
DAGIAFAPVY SMGAPSSKSG RTMPNILDDI IASVVENKIP PSKTSKINVK PELKEELEES
IISAVDENNK LYSDIPHSWI CEKHILWLKD YKNSNNWKLF KECWKQGQPA VVSGVHKKMN
ISLWKAESIS LDFGDHQADL LNCKDSIISN ANVKEFWDGF EEVSKRQKNK SGETVVLKLK
DWPSGEDFKT MMPARYEDLL KSLPLPEYCN PEGKFNLASH LPGFFVRPDL GPRLCSAYGV
VAAKDHDIGT TNLHIEVSDV VNILVYVGIA KGNGILSKAG ILKKFEEEDL DDILRKRLKD
SSEIPGALWH IYAGKDVDKI REFLQKISKE QGLEVLPEHD PIRDQSWYVN KKLRQRLLEE
YGVRTCTLIQ FLGDAIVLPA GALHQVQNFH SCIQVTEDFV SPEHLVESFH LTQELRLLKE
EINYDDKLQV KNILYHAVKE MVRALKIHED EVEDMEEN
//
