ID A0A2K5X9E7_MACFA Unreviewed; 382 AA.
AC A0A2K5X9E7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=CEA cell adhesion molecule 8 {ECO:0000313|Ensembl:ENSMFAP00000046090.2};
GN Name=CEACAM8 {ECO:0000313|Ensembl:ENSMFAP00000046090.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000046090.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000046090.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000046090.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. CEA family.
CC {ECO:0000256|ARBA:ARBA00038222}.
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DR AlphaFoldDB; A0A2K5X9E7; -.
DR STRING; 9541.ENSMFAP00000046090; -.
DR Ensembl; ENSMFAT00000020395.2; ENSMFAP00000046090.2; ENSMFAG00000000741.2.
DR VEuPathDB; HostDB:ENSMFAG00000000741; -.
DR GeneTree; ENSGT01100000263479; -.
DR Proteomes; UP000233100; Chromosome 19.
DR Bgee; ENSMFAG00000000741; Expressed in colon and 1 other cell type or tissue.
DR CDD; cd20948; IgC2_CEACAM5-like; 1.
DR CDD; cd05740; IgI_hCEACAM_2_4_6_like; 1.
DR CDD; cd05774; IgV_CEACAM_D1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR44427; CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19; 1.
DR PANTHER; PTHR44427:SF20; CEA CELL ADHESION MOLECULE 8; 1.
DR Pfam; PF13895; Ig_2; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000233100}.
FT DOMAIN 178..265
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 273..352
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 171..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 382 AA; 41390 MW; 735B65856C9C40C0 CRC64;
MGAADLDSVG DTHTHTHTHT HTHNHNHKLQ SKSPHFSTPN TQVVILIDVL YPILASLFTF
WNPPTTAQLT IEAVPSNAAE GKEVLLLVHN LPQDPLGYNW YKGETVDANR RIIGYVIATQ
VNISGPADSG RETIYPNATL LMQNVTRNDT GSYTLQVITL NLVNEEVTGQ FSVHPETPKP
SISSNNSNPV EDRDAVALTC EPETQNTTYL WWVNGQSLPV SPRLQLSDGN RTLTLLNVTR
NDTGPYECEI QNPVSVNFSD PVTLNVLYGP DAPNISPSDT YYLPGVNLNL SCHAASNPLA
QYSWSVNGTF QQHTQNLFIP NITAKNSGSY ACHATNSATG HNGTTVRMIT VSDASVQGSS
PGLSARATVS IMIGILARVA LT
//
