ID A0A2K5XA95_MANLE Unreviewed; 218 AA.
AC A0A2K5XA95;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Zinc finger BED-type containing 2 {ECO:0000313|Ensembl:ENSMLEP00000000140.1};
GN Name=ZBED2 {ECO:0000313|Ensembl:ENSMLEP00000000140.1};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000000140.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000000140.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_011825124.1; XM_011969734.1.
DR AlphaFoldDB; A0A2K5XA95; -.
DR STRING; 9568.ENSMLEP00000000140; -.
DR Ensembl; ENSMLET00000000333.1; ENSMLEP00000000140.1; ENSMLEG00000000313.1.
DR GeneID; 105531746; -.
DR KEGG; mleu:105531746; -.
DR CTD; 79413; -.
DR GeneTree; ENSGT00940000163343; -.
DR OMA; GHHPNQY; -.
DR OrthoDB; 4613048at2759; -.
DR Proteomes; UP000233140; Unplaced.
DR GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0045618; P:positive regulation of keratinocyte differentiation; IEA:Ensembl.
DR InterPro; IPR043471; ZBED2/3.
DR InterPro; IPR003656; Znf_BED.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR PANTHER; PTHR35827:SF1; ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR35827; ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 3; 1.
DR Pfam; PF02892; zf-BED; 1.
DR SMART; SM00614; ZnF_BED; 1.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR PROSITE; PS50808; ZF_BED; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00027}.
FT DOMAIN 52..113
FT /note="BED-type"
FT /evidence="ECO:0000259|PROSITE:PS50808"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 104..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 104..118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 218 AA; 25038 MW; 409D4A08B78FE34C CRC64;
MMRREEEEEE GAMMKAKGDL EMKEEEEISE IGELVGPFVS AMPTPTPHNK GTRFSEAWEY
FHLAPARAGH HPNQYATCRL CGRQVSRGPG VNVGTTALWK HLKSMHREEL EKSGHGQAGQ
RQDPRPHGPQ LPTGIEGDWG RLLEQVGTMA LWASQREKEV LRREMAVEWR ERAVEKRERA
LEEVERAILE MKWKVRAEKE VCQQEKELPA AVHAFHFV
//
