ID A0A2K5XNP5_MANLE Unreviewed; 512 AA.
AC A0A2K5XNP5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=V-set and immunoglobulin domain containing 10 {ECO:0000313|Ensembl:ENSMLEP00000004927.1};
GN Name=VSIG10 {ECO:0000313|Ensembl:ENSMLEP00000004927.1};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000004927.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000004927.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR AlphaFoldDB; A0A2K5XNP5; -.
DR STRING; 9568.ENSMLEP00000004927; -.
DR Ensembl; ENSMLET00000024376.1; ENSMLEP00000004927.1; ENSMLEG00000022365.1.
DR GeneTree; ENSGT00940000159876; -.
DR OMA; GASCMVQ; -.
DR Proteomes; UP000233140; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR CDD; cd00096; Ig; 1.
DR CDD; cd00099; IgV; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR11640; NEPHRIN; 1.
DR PANTHER; PTHR11640:SF157; V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 10; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 3.
DR SMART; SM00406; IGv; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 387..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..80
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 99..191
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 199..283
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 287..380
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 439..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 486..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 439..456
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 512 AA; 56259 MW; CCAB3D0755B32D58 CRC64;
MDGLEAVVIG EVHENVTLHC GNISGPRGLV TWYRNDSEPV FLLSSNSSLP PAEPRFSLVD
ASSLHIKSLG LGDEGNYTCQ EILNVTQWFQ VWLQVASGPY QIEVHIAATG TLPNGTLYAA
RGSGVDFSCN SSSRPPPMVE WWFQALNSSS ESFGHNLTVN SFSLLLMSPN LQGNYTCLAL
NLLSKRHRKV TTELLVYYPP PSAPQCWAQM ASGSFMLQLT CRWDGGYPDP DFLWIEEPGG
VIVGKSKLGV EMLSESQLSD GKKFKCVTSH IVGPASGASC VVQIRGPSLL SEPMKTCFVG
GNVTLTCQVS GAYPPAKILW LRNLTQPEVV IQPSSRHLIT QDGQDSTLTI HNCSQDLDEG
YYICRADSPV GVREVEIWLS VKEPVNIGGI VGTIVSLLLL GLAIISGLLL YYSPVFCWKV
GNTFRGQNMD DVMVLVDSEE EEEEEEDAAV EEEEEAHERE ELPKEIPKQD HIHRVTALVN
GNIEQMGNGF QDLQDDSSEE QSDIVQEEDR PV
//
