ID   A0A2K5XRI1_MANLE        Unreviewed;       444 AA.
AC   A0A2K5XRI1;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=Spermatogenesis-defective protein 39 homolog {ECO:0000256|ARBA:ARBA00019368};
DE   AltName: Full=VPS33B-interacting protein in apical-basolateral polarity regulator {ECO:0000256|ARBA:ARBA00029984};
DE   AltName: Full=VPS33B-interacting protein in polarity and apical restriction {ECO:0000256|ARBA:ARBA00031270};
GN   Name=VIPAS39 {ECO:0000313|Ensembl:ENSMLEP00000005922.1};
OS   Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Mandrillus.
OX   NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000005922.1, ECO:0000313|Proteomes:UP000233140};
RN   [1] {ECO:0000313|Ensembl:ENSMLEP00000005922.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Early endosome {ECO:0000256|ARBA:ARBA00004412}.
CC       Endosome {ECO:0000256|ARBA:ARBA00004177}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_011843670.1; XM_011988280.1.
DR   AlphaFoldDB; A0A2K5XRI1; -.
DR   Ensembl; ENSMLET00000027880.1; ENSMLEP00000005922.1; ENSMLEG00000024785.1.
DR   GeneID; 105545363; -.
DR   CTD; 63894; -.
DR   GeneTree; ENSGT00390000013955; -.
DR   OMA; YWNRSSR; -.
DR   OrthoDB; 2945298at2759; -.
DR   Proteomes; UP000233140; Unplaced.
DR   GO; GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0032991; C:protein-containing complex; IEA:UniProt.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   Gene3D; 1.10.150.780; Vps16, C-terminal region; 1.
DR   InterPro; IPR040057; Spe-39.
DR   InterPro; IPR006925; Vps16_C.
DR   InterPro; IPR038132; Vps16_C_sf.
DR   PANTHER; PTHR13364; DEFECTIVE SPERMATOGENESIS PROTEIN 39; 1.
DR   PANTHER; PTHR13364:SF6; SPERMATOGENESIS-DEFECTIVE PROTEIN 39 HOMOLOG; 1.
DR   Pfam; PF04840; Vps16_C; 2.
PE   4: Predicted;
KW   Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW   Endosome {ECO:0000256|ARBA:ARBA00022753};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233140}.
FT   DOMAIN          128..228
FT                   /note="Vps16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04840"
FT   DOMAIN          308..416
FT                   /note="Vps16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04840"
FT   REGION          40..100
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        65..82
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   444 AA;  51535 MW;  C262CB9896B89197 CRC64;
     MNRTKGDEEE YWNSSKFKAF TFDDEDDELS QLKESKRAVN SLRDFVDDDD DDDLERVSWS
     GEPVGSRTRP GSFQSLSDAL SDTPAKSYAP ELGRPKGEYR DYSNDWSPSD TVRRLRKGKV
     CSLERFRSLQ DKLQLLEEAV SMHDGNVITA VLIFLKRTLS KEILFRELEV RQVALRHLIH
     FLKEIGDQKL LLDLFRFLDR TEELALSHYR EHLNIQDPDK RKEFLKTCIG LPFSAEDSAH
     IQDHYTLLER QIIIEANDRH LESAGQTEIF RKHPRKASIL NMPLVTTLFY SCFYHYTEAE
     GTFSSPVNLK KTFKIPDKQY VLTALAARAK LRAWNDVDAL FTTKNWLGYT KKRAPIGFHR
     VVEILHKNNA PVQILQEYVN LVEDVDTKLN LATKFKCHDV VIDTCRDLKD RQQLLAYRSK
     VDKGSAEEEK IDALLSSSQI RWKN
//