ID   A0A2K5XT51_MANLE        Unreviewed;       604 AA.
AC   A0A2K5XT51;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   RecName: Full=Transporter {ECO:0000256|RuleBase:RU003732};
GN   Name=SLC6A11 {ECO:0000313|Ensembl:ENSMLEP00000006492.1};
OS   Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Mandrillus.
OX   NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000006492.1, ECO:0000313|Proteomes:UP000233140};
RN   [1] {ECO:0000313|Ensembl:ENSMLEP00000006492.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the sodium:neurotransmitter symporter (SNF) (TC
CC       2.A.22) family. {ECO:0000256|RuleBase:RU003732}.
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DR   AlphaFoldDB; A0A2K5XT51; -.
DR   Ensembl; ENSMLET00000029431.1; ENSMLEP00000006492.1; ENSMLEG00000026707.1.
DR   GeneTree; ENSGT00940000157569; -.
DR   Proteomes; UP000233140; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR   GO; GO:0005332; F:gamma-aminobutyric acid:sodium:chloride symporter activity; IEA:InterPro.
DR   GO; GO:0006836; P:neurotransmitter transport; IEA:InterPro.
DR   CDD; cd11508; SLC6sbd_GAT3; 1.
DR   InterPro; IPR000175; Na/ntran_symport.
DR   InterPro; IPR002982; Na/ntran_symport_GABA_GAT3.
DR   InterPro; IPR037272; SNS_sf.
DR   PANTHER; PTHR11616:SF124; SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 3; 1.
DR   PANTHER; PTHR11616; SODIUM/CHLORIDE DEPENDENT TRANSPORTER; 1.
DR   Pfam; PF00209; SNF; 1.
DR   PRINTS; PR01197; GAT3TRNSPORT.
DR   PRINTS; PR00176; NANEUSMPORT.
DR   SUPFAM; SSF161070; SNF-like; 1.
DR   PROSITE; PS00610; NA_NEUROTRAN_SYMP_1; 1.
DR   PROSITE; PS00754; NA_NEUROTRAN_SYMP_2; 1.
DR   PROSITE; PS50267; NA_NEUROTRAN_SYMP_3; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW   Symport {ECO:0000256|RuleBase:RU003732};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU003732};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003732}.
FT   TRANSMEM        58..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        115..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        227..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        270..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        307..333
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        410..435
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        441..465
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        486..505
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        525..546
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   604 AA;  68096 MW;  6FE58DE617EA3D41 CRC64;
     HNTNNSYWPS VVAHRDKAVH ERGHWNNKVE FVLSVAGEII GLGNVWRFPY LCYKNGGGAF
     LIPYVVFFIC CGIPVFFLET ALGQFTSEGG ITCWRKVCPL FEGIGYATQV IEAHLNVYYI
     IILAWAIFYL SNCFTTELPW ATCGHEWNTE NCVEFQKLNV SNYSHVSLQN ATSPVMEFWE
     RRVLAISDGI EHIGNLRWEL ALCLLAAWTI CYFCIWKGTK STGKVVYVTA TFPYIMLLIL
     LIRGVTLPGA SEGIKFYLYP DISRLSDPQV WVDAGTQIFF SYAICLGCLT ALGSYNNYNN
     NCYRDCIMLC CLNSGTSFVA GFAIFSVLGF MAYEQGVPIA EVAESGPGLA FIAYPKAVTM
     MPLSPLWATL FFMMLIFLGL DSQFVCVESL VTAVVDMYPK VFRRGYRREL LILALSVISY
     FLGLVMLTEG GMYIFQLFDS YAASGMCLLF VAIFECICIG WVYGSNRFYD NIEDMIGYRP
     PSLIKWCWKI VTPGICAGIF IFFLVKYKPL KYNNVYTYPA WGYGIGWLMA LSSMLCIPLW
     ICIKVWKTQG TLPEKLQKLT TPSTDLKMRG KLGVSPRMVT VNDCDAKLKS DGTIAAITEK
     ETHF
//