ID A0A2K5XUR5_MANLE Unreviewed; 502 AA.
AC A0A2K5XUR5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Zinc finger C3HC-type containing 1 {ECO:0000313|Ensembl:ENSMLEP00000007042.1};
GN Name=ZC3HC1 {ECO:0000313|Ensembl:ENSMLEP00000007042.1};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000007042.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000007042.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_011851258.1; XM_011995868.1.
DR AlphaFoldDB; A0A2K5XUR5; -.
DR STRING; 9568.ENSMLEP00000007042; -.
DR Ensembl; ENSMLET00000030319.1; ENSMLEP00000007042.1; ENSMLEG00000027328.1.
DR GeneID; 105550825; -.
DR KEGG; mleu:105550825; -.
DR CTD; 51530; -.
DR GeneTree; ENSGT00390000006086; -.
DR OrthoDB; 1041481at2759; -.
DR Proteomes; UP000233140; Unplaced.
DR GO; GO:0031965; C:nuclear membrane; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0019901; F:protein kinase binding; IEA:Ensembl.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR InterPro; IPR013909; NIPA/Rsm1_C.
DR InterPro; IPR012935; Znf_C3HC-like.
DR PANTHER; PTHR15835; NUCLEAR-INTERACTING PARTNER OF ALK; 1.
DR PANTHER; PTHR15835:SF6; ZINC FINGER C3HC-TYPE PROTEIN 1; 1.
DR Pfam; PF08600; Rsm1; 1.
DR Pfam; PF07967; zf-C3HC; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 73..199
FT /note="C3HC-type"
FT /evidence="ECO:0000259|Pfam:PF07967"
FT DOMAIN 248..334
FT /note="Nuclear-interacting partner of ALK/Rsm1-like C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08600"
FT REGION 22..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 302..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..359
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..422
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 502 AA; 55207 MW; 695CD088C067AFC9 CRC64;
MAAPSEGQAF AVGVEKNWGA VVRSPEGTPQ KIRQLIDEGI APEEGGVDAK DTSATSQSVN
GSPQAEQPSL ESTSKEAFFS RVETFSSLKW AGKPPELSPL VCAKYGWVTV ECDMLKCSSC
QAFLCASLQP AFDFDRYKQR CAELKKALCT AHEKFCFWPD SPSPDRFGML PLDEPAILVS
EFLDRFQSLC HLDLQLPSLR PEDLKTMCLT EDKLSLLLHL LEDELDHRTD ERKTTIKLGS
DIQVHVTACI LSVCGWACSS SLEPMQLSLI TCSQCMRKVG LWGFQQIESS MTDLDASFGL
TSSPIPGLEG RPERLPLVPE SPRRMMTRSQ DATFSPGSEQ AEKSPGPIVS RTRSWDSSSP
VDRPEPEAAS PTTRTRPVTR SMGTGDTPGM EVPSSPLRKA KRARLCSSSS SDTSSRSFFD
PTSQHRDWCP WVNITLGKES RENGGTEPDA SAPAEPGWKA VLTILLAHKQ SSQPAETDSM
SLSEKSRKVF RIFRQWESLC SS
//
