ID A0A2K5XUZ8_MANLE Unreviewed; 283 AA.
AC A0A2K5XUZ8;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Peflin {ECO:0000256|ARBA:ARBA00041025};
DE AltName: Full=PEF protein with a long N-terminal hydrophobic domain {ECO:0000256|ARBA:ARBA00041490};
DE AltName: Full=Penta-EF hand domain-containing protein 1 {ECO:0000256|ARBA:ARBA00042606};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000007105.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000007105.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, COPII-coated vesicle
CC membrane {ECO:0000256|ARBA:ARBA00037873}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00037873}.
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DR RefSeq; XP_011829408.1; XM_011974018.1.
DR AlphaFoldDB; A0A2K5XUZ8; -.
DR STRING; 9568.ENSMLEP00000007105; -.
DR Ensembl; ENSMLET00000030384.1; ENSMLEP00000007105.1; ENSMLEG00000027504.1.
DR GeneID; 105535045; -.
DR KEGG; mleu:105535045; -.
DR CTD; 553115; -.
DR GeneTree; ENSGT00940000155722; -.
DR OrthoDB; 318691at2759; -.
DR Proteomes; UP000233140; Unplaced.
DR GO; GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048306; F:calcium-dependent protein binding; IEA:UniProt.
DR CDD; cd16184; EFh_PEF_peflin; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR46212; PEFLIN; 1.
DR PANTHER; PTHR46212:SF3; PEFLIN; 1.
DR Pfam; PF13405; EF-hand_6; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00054; EFh; 3.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 113..148
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 180..215
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 46..63
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 283 AA; 30308 MW; 7237F9E55FB54343 CRC64;
MASYPYRQGC PGAAGQAPGA PPGSYYPGPP NSGGQYGSGL PPGGYGGPAP GGPYGPPAGG
GPYGHPNPGM FPSGTPGGPY GGAAPGGPYG QPPPSSYGAQ QPGPYGQGGA PPNVDPEAYS
WFQSVDSDHS GYISMKELKQ ALVNCNWSSF NDETCLMMIN MFDKTKSGRI DVYGFSALWK
FIQQWKNLFQ QYDRDRSGSI SYTELQQALS QMGYNLSPQF TQLLVSRYCP RSANPAMQLD
RFIQVCTQLQ VLTEAFREKD TAVQGNIRLS FEDFVTMTAS RML
//
