ID   A0A2K5XV65_MANLE        Unreviewed;       427 AA.
AC   A0A2K5XV65;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Regulator of chromosome condensation 2 {ECO:0000313|Ensembl:ENSMLEP00000007175.1};
GN   Name=RCC2 {ECO:0000313|Ensembl:ENSMLEP00000007175.1};
OS   Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Mandrillus.
OX   NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000007175.1, ECO:0000313|Proteomes:UP000233140};
RN   [1] {ECO:0000313|Ensembl:ENSMLEP00000007175.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K5XV65; -.
DR   STRING; 9568.ENSMLEP00000007175; -.
DR   Ensembl; ENSMLET00000030470.1; ENSMLEP00000007175.1; ENSMLEG00000027564.1.
DR   GeneTree; ENSGT00940000156151; -.
DR   OMA; GKWKNTG; -.
DR   Proteomes; UP000233140; Unplaced.
DR   GO; GO:0034506; C:chromosome, centromeric core domain; IEA:Ensembl.
DR   GO; GO:0031901; C:early endosome membrane; IEA:Ensembl.
DR   GO; GO:0030496; C:midbody; IEA:Ensembl.
DR   GO; GO:1990023; C:mitotic spindle midzone; IEA:Ensembl.
DR   GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   GO; GO:0008017; F:microtubule binding; IEA:Ensembl.
DR   GO; GO:0019904; F:protein domain specific binding; IEA:Ensembl.
DR   GO; GO:0019901; F:protein kinase binding; IEA:Ensembl.
DR   GO; GO:0031267; F:small GTPase binding; IEA:Ensembl.
DR   GO; GO:0072356; P:chromosome passenger complex localization to kinetochore; IEA:Ensembl.
DR   GO; GO:0045184; P:establishment of protein localization; IEA:Ensembl.
DR   GO; GO:0048041; P:focal adhesion assembly; IEA:Ensembl.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0051895; P:negative regulation of focal adhesion assembly; IEA:Ensembl.
DR   GO; GO:1900025; P:negative regulation of substrate adhesion-dependent cell spreading; IEA:Ensembl.
DR   GO; GO:0051987; P:positive regulation of attachment of spindle microtubules to kinetochore; IEA:Ensembl.
DR   GO; GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0010762; P:regulation of fibroblast migration; IEA:Ensembl.
DR   GO; GO:1900027; P:regulation of ruffle assembly; IEA:Ensembl.
DR   Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 2.
DR   InterPro; IPR009091; RCC1/BLIP-II.
DR   InterPro; IPR028641; RCC2.
DR   InterPro; IPR000408; Reg_chr_condens.
DR   PANTHER; PTHR46207; PROTEIN RCC2; 1.
DR   PANTHER; PTHR46207:SF1; PROTEIN RCC2; 1.
DR   Pfam; PF00415; RCC1; 4.
DR   PRINTS; PR00633; RCCNDNSATION.
DR   SUPFAM; SSF50985; RCC1/BLIP-II; 1.
DR   PROSITE; PS00626; RCC1_2; 2.
DR   PROSITE; PS50012; RCC1_3; 5.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233140}.
FT   REPEAT          74..125
FT                   /note="RCC1"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT   REPEAT          126..177
FT                   /note="RCC1"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT   REPEAT          178..253
FT                   /note="RCC1"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT   REPEAT          254..307
FT                   /note="RCC1"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT   REPEAT          353..407
FT                   /note="RCC1"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT   REGION          407..427
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   427 AA;  46611 MW;  C38016E76D33DB1D CRC64;
     KLEGSKCKGQ LLIFGATNWD LIGRKEVPKQ QAAYRNLGQN LWGPHRYGCL AGVRVRTVVS
     GSCAAHSLLI TTEGKLWSWG RNEKGQLGHG DTKRVEAPRL IEGLSHEVIV SAACGRNHTL
     ALTETGSVFA FGENKMGQLG LGNQTDAVPS PAQIMYNGQP ITKMACGAEF SMIMDCKGNL
     YSFGCPEYGQ LGHNSDGKFI ARAQRIEYDC ELVPRRVAIF IEKTKDGQIL PVPNVVVRDV
     ACGANHTLVL DSQKRVFSWG FGGYGRLGHA EQKDEMVPRL VKLFDFPGRG ASQIYAGYTC
     SFAVSEVGGL FFWGATNTSR ESTMYPKAVQ DLCGWRIRSL ACGKSSIIVA ADESTISWGP
     SPTFGELGYG DHKPKSSTAA QEVKTLDGIF SEQVAMGYSH SLVIARDESE TEKEKIKKLP
     EYNPRTL
//