ID A0A2K5XWW3_MANLE Unreviewed; 637 AA.
AC A0A2K5XWW3;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Zinc finger protein 44 {ECO:0000313|Ensembl:ENSMLEP00000007812.1};
GN Name=ZNF44 {ECO:0000313|Ensembl:ENSMLEP00000007812.1};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000007812.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000007812.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR AlphaFoldDB; A0A2K5XWW3; -.
DR STRING; 9568.ENSMLEP00000007812; -.
DR Ensembl; ENSMLET00000031165.1; ENSMLEP00000007812.1; ENSMLEG00000028038.1.
DR GeneTree; ENSGT00950000182755; -.
DR OMA; VWPSLFQ; -.
DR Proteomes; UP000233140; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 16.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24409:SF448; ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 17; 1.
DR PANTHER; PTHR24409; ZINC FINGER PROTEIN 142; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 13.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 16.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 9.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 14.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 16.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 33..112
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 191..218
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 219..246
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 247..274
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 275..302
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 303..330
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 331..358
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 359..386
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 387..414
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 415..442
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 443..470
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 471..497
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 498..525
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 526..553
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 554..581
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 582..609
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 610..632
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 637 AA; 73820 MW; ECDB18032C1D1B00 CRC64;
TFWGYPKLTP WVTLPRGQSE VLGWGLPKDQ DSVAFEDVAV NFTHEEWALL GPSQKNLYRD
VMRETIRNLN CVGMDDIINV LFVFYRCDVV ERFGKSKDGS QCEETLSQIR NSTVNKNTPA
RVDACESSVN GEVIMGHSSL NCYIRVDTGH KHRECHEYAE KPYTHKQCGK GLSYRHSFRT
RERPYTGKKP YDCKECGKTF SSPGNLRRHM VVQGGDGPYK CELCGKAFFW PSLLRMHERT
HTGEKPYECK HCSKAFPVYS SYLRHEKIHT GEKPYECKQC SKAFPDYSSY LRHERTHTGE
KPYKCEQCGK AFSVSGSLRV HERIHTGEKP YTCKQCGKAF CHLGSFQRHM IMHSGDGPHK
CKICGKGFDF PGSARIHEGT HTLEKPYECK QCGKLLSHRS SFRRHMMAHT GDGPHKCMVC
GKAFDSPSVF QRHERTHTGE KPYECKQCGK AFRISSSLRK HETTHTGEQP YKCKCGKAFS
DFFSFQSHET THSEEEPYEC KECGKAFSSF KYFCRHERTH SEEKSYECQT CGKAFSRFSY
LKTHERTHTA EKPYECKQCR KAFFWPSFLL RHERTHTGER PYECKHCGKA FSRSSFCREH
ERTHTGEKPY ECKECGKAFS SLSSFNRHKR THWKDIL
//
