ID A0A2K5Y1R0_MANLE Unreviewed; 502 AA.
AC A0A2K5Y1R0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Adhesion G protein-coupled receptor G7 {ECO:0000313|Ensembl:ENSMLEP00000009445.1};
GN Name=ADGRG7 {ECO:0000313|Ensembl:ENSMLEP00000009445.1};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000009445.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000009445.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A2K5Y1R0; -.
DR Ensembl; ENSMLET00000032846.1; ENSMLEP00000009445.1; ENSMLEG00000028901.1.
DR GeneTree; ENSGT00940000159169; -.
DR OMA; MSFKINY; -.
DR Proteomes; UP000233140; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR CDD; cd15257; 7tmB2_GPR128; 1.
DR Gene3D; 2.60.220.50; -; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR046338; GAIN_dom_sf.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR047938; GPR128_7tmB2.
DR InterPro; IPR000203; GPS.
DR PANTHER; PTHR47767; ADHESION G PROTEIN-COUPLED RECEPTOR G7; 1.
DR PANTHER; PTHR47767:SF1; ADHESION G-PROTEIN COUPLED RECEPTOR G7; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF01825; GPS; 1.
DR PRINTS; PR00249; GPCRSECRETIN.
DR SMART; SM00303; GPS; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS50221; GPS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..502
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014470182"
FT TRANSMEM 141..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 139..429
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
SQ SEQUENCE 502 AA; 57335 MW; 0FA3F43B988337FB CRC64;
MPVEMLFKKL LLLLIMMPLQ RNSKACGFVV YQNDKLFQSK TFTAKSNFSQ KIISSKTDEN
EQDQSASVDM VFSPRYNQRE FQLYSYACVY WNLSTRDWDT YGCQKHKGTD GFLRCHCNHT
TNFAVLMTFK KDYQYPKSLD VFSNVGCALS ITGLALTIVF QIVTRKVRKT SVTWVLVNLC
ISMLIFNLLF VFGIENSNKN NKTSDGDIHD IDFKNNDVPQ TDTINTPNPT CTAIAALLHY
FLLVTFTWNA LSAAQLYFLL IRTMKPLPRH FILFISLIGW GVPAIVVAIT VGVIYSQNGK
NPQWELDYRQ EIICWLAIPE PDGVTKSPLL WSFIVPVTII LISNVVIFIT ISIKVLWKNN
QNLTSTKKVS SMRKIVSTLS VAVVFGITWI LAYLMLVNDD SIRIIFSYIF CLFNTTQGLQ
IFILYTVRTK IFQTEASKVL TLLSSIGGKK SLSSVTRLRL RVRMYNFLRS LPTLHEHFRL
LETSLSTEDI TLSESDKAKE SI
//
