ID   A0A2K5Y8T5_MANLE        Unreviewed;       458 AA.
AC   A0A2K5Y8T5;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Chemokine interleukin-8-like domain-containing protein {ECO:0000259|SMART:SM00199};
OS   Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Mandrillus.
OX   NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000011965.1, ECO:0000313|Proteomes:UP000233140};
RN   [1] {ECO:0000313|Ensembl:ENSMLEP00000011965.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the intercrine alpha (chemokine CxC) family.
CC       {ECO:0000256|ARBA:ARBA00010665}.
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DR   AlphaFoldDB; A0A2K5Y8T5; -.
DR   STRING; 9568.ENSMLEP00000011965; -.
DR   Ensembl; ENSMLET00000035391.1; ENSMLEP00000011965.1; ENSMLEG00000030159.1.
DR   GeneTree; ENSGT00390000014056; -.
DR   Proteomes; UP000233140; Unplaced.
DR   GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR   GO; GO:0008009; F:chemokine activity; IEA:InterPro.
DR   GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   CDD; cd00273; Chemokine_CXC; 1.
DR   Gene3D; 2.40.50.40; -; 1.
DR   InterPro; IPR001811; Chemokine_IL8-like_dom.
DR   InterPro; IPR033899; CXC_Chemokine_domain.
DR   InterPro; IPR036048; Interleukin_8-like_sf.
DR   Pfam; PF00048; IL8; 1.
DR   SMART; SM00199; SCY; 1.
DR   SUPFAM; SSF54117; Interleukin 8-like chemokines; 1.
PE   3: Inferred from homology;
KW   Cytokine {ECO:0000256|ARBA:ARBA00022514};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Inflammatory response {ECO:0000256|ARBA:ARBA00023198};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT   DOMAIN          345..404
FT                   /note="Chemokine interleukin-8-like"
FT                   /evidence="ECO:0000259|SMART:SM00199"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   458 AA;  49380 MW;  CF185E174ABE66B4 CRC64;
     MEPLTAGLAG QPTPRWPGLP RARDVSPGQA PGCTRRLTPL RWTLCGEGHR EVAGAARGHK
     ERPKGALSSP PRLLVERSEL QKLYSRLLTA AGAFCFVQVR KLRLGWWRHG LGVRATLTAK
     TGLIPADQAP LAGQVASLSP HAQKAGPPRL PWTAAASSPS APGAIRLLFI GSHSVPAIER
     PHPAAFHALP TFLLRSSVSP AGPCHRDNKR PSSRRHPGCG PHCRPGLRRG LCGPSAPQAL
     DWVRADAAPA SSLAVDCALI LEGFLKTPGA KLTGSQIRGT IRASQDFCQY TDLHPERLGN
     LEGPKRNPGK PGGTTLREER LAPQLPRLQA GALVVVFPGK PVSLSYRCPC RFFESHVARA
     NVKHLKILNT PNCALQIVAR LKNNNRQVCI DPKLKWIQEY LEKALNNLIS AAPAGKRVIA
     GAHALHPSPP RACSPARALC EIYLWPPPEW SWPCPGDV
//