ID A0A2K5Y9P3_MANLE Unreviewed; 588 AA.
AC A0A2K5Y9P3;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Ankyrin repeat and SOCS box containing 15 {ECO:0000313|Ensembl:ENSMLEP00000012277.1};
GN Name=ASB15 {ECO:0000313|Ensembl:ENSMLEP00000012277.1};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000012277.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000012277.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the ankyrin SOCS box (ASB) family.
CC {ECO:0000256|ARBA:ARBA00005949}.
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DR RefSeq; XP_011851337.1; XM_011995947.1.
DR RefSeq; XP_011851338.1; XM_011995948.1.
DR AlphaFoldDB; A0A2K5Y9P3; -.
DR STRING; 9568.ENSMLEP00000012277; -.
DR Ensembl; ENSMLET00000035705.1; ENSMLEP00000012277.1; ENSMLEG00000030309.1.
DR GeneID; 105550882; -.
DR KEGG; mleu:105550882; -.
DR CTD; 142685; -.
DR GeneTree; ENSGT00940000157073; -.
DR OMA; HVNDTHF; -.
DR OrthoDB; 5479200at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000233140; Unplaced.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03731; SOCS_ASB15; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24126:SF14; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 10-RELATED; 1.
DR PANTHER; PTHR24126; ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED; 1.
DR Pfam; PF12796; Ank_2; 3.
DR Pfam; PF13606; Ank_3; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 9.
DR SMART; SM00253; SOCS; 1.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 7.
DR PROSITE; PS50088; ANK_REPEAT; 7.
DR PROSITE; PS50225; SOCS; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 110..142
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 143..171
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 176..208
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 209..241
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 307..339
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 349..381
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 379..407
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 533..579
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 588 AA; 65917 MW; 6C1311F984DDAC4A CRC64;
MDTNDDPDED HLTSYDIQLS IQESIEASKT ALYPERFVPL SGQNRKLVEA IKQGHILELQ
EYVKYKYAMD EADEKGWFPL HEAVVQPIQQ ILEIVLDASY KTLWEFKTCD GETPLTLAVK
AGLVKNVRTL LEKGVWPNTK NDKGETPLLI AVKKGSYDMV STLIKHNTSL DQPCVKRWSA
MHEAAKQGRK DIISLLLKHG GNVHLRDGFG VTPLGVAAEY GHCDVLEHLI HKGGDVLALA
DDGASVMFEA AGGGNPDCIS LLLEYGGSGN VPNRAGHLPI HRAAYEGHYL ALKYLIPATS
KNAIRKSGLT PIHSAADGQS AQCLELLIEN GFDVNTLLAD HISQSYDDER KTALYFAVSN
NDVRCTEVLL AAGADPNLDP LNCLLVAVRA NNYEIVRLLL SHGANVNCYF MHVNDTRFPS
VIQYALNDEV MLRLLLNNGY QVEMCFDCMH GDIFGNSFVW SETEEEVLPG WTSCVIKDNP
FCEFITVPWM KHLVGRVTRI LIDYMDYVPL CAKLKSALEV QREWPEIRQI LENPCSLKHL
CRLKIRRLMG LQKLCQPASM EKLPLPPAIQ RYILFKEYDL YGQELKLP
//
