ID A0A2K5YH25_MANLE Unreviewed; 2357 AA.
AC A0A2K5YH25;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Jumonji domain containing 1C {ECO:0000313|Ensembl:ENSMLEP00000014856.1};
GN Name=JMJD1C {ECO:0000313|Ensembl:ENSMLEP00000014856.1};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000014856.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000014856.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR Ensembl; ENSMLET00000038308.1; ENSMLEP00000014856.1; ENSMLEG00000031563.1.
DR GeneTree; ENSGT00940000158210; -.
DR Proteomes; UP000233140; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0032454; F:histone H3K9 demethylase activity; IEA:InterPro.
DR Gene3D; 2.60.120.650; Cupin; 1.
DR InterPro; IPR045109; JHDM2-like.
DR InterPro; IPR003347; JmjC_dom.
DR PANTHER; PTHR12549; JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN; 1.
DR PANTHER; PTHR12549:SF6; JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 2C-RELATED; 1.
DR Pfam; PF02373; JmjC; 1.
DR SMART; SM00558; JmjC; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51184; JMJC; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233140}.
FT DOMAIN 2091..2315
FT /note="JmjC"
FT /evidence="ECO:0000259|PROSITE:PS51184"
FT REGION 96..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 449..477
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1061..1081
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1431..1509
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1788..1881
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..128
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..274
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 275..299
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1431..1500
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1788..1822
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1832..1863
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1864..1881
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2357 AA; 263129 MW; 08AB8DC56F756BB7 CRC64;
LQSPYSLNGY RVRVYRQDSA TQWFTGIITH HDLFTRTMIV MNDQVLEPQN VDPSMVQMTF
LDDVVHSLLK GENIGITSRR RSRANQNVNA VHSHYTRAQA NSPRPAMNSQ AAVPKQNTHQ
QQQQRSIRPN KRKGSDSSIP DEEKMKEEKY DYISRGENPK GKNKHLMNKR RKPEEDEKKL
NMKRLRTDNV SDFSESSDSE NSNKRIIDNS SEQKSENELK NKNTSKINGE EGKPHNNEKA
GEETLKDSQP PWDQIQEDKK HEEAEKRKSV DTQLQEDMII HSSEQSTVSD HNSNDLLPQE
CSMEKTHTME LLPKEKFVSR PPTPKCVIDI TNDTNLEKVA QESSSTFGLQ TLQKMDPNVS
DSKHSIANAK FLETAKQDSD QSWVSDVVKV DLTQSSVTNA SSGNDHLNME KEKYVSYISP
LSAVSVMEDK LHKRSPPPET IKSKLNTSVD THKIKSSPSP EVVKPKITHS PDSVKSKTTY
VNSQATGERR LANKIEHELS RCSFHPIPTR SSTLENTKSP LIIDKNEHFT VYRDPALIGS
ETGANHISPF LSQHPFPLHS SSHRTCLNPG THHPALTPAP HLLAGSSSQT PLPTINTHPL
TSGPHHAVHH PHLLPTVLPG VPTASLLGGH PRLESAHASS LSHLALAHQQ QQQLLQHQSP
HLLGQAHPSA SYNQLGLYPI IWQYPNGTHA YSGLGLPSSK WVHPENAVNA EASLRRNSPS
PWLHQPTPVT SADGIGLLSH IPVRPSSAEP HRPLKITAHS SPPLTKTLVD HHKEELERKA
FMEPLRSVAS TSAKNDLDLN RSQTGKDCHF HRHFVDPVLN QLQRPPQETG ERLNKYKEEH
RRILQESIDV APFTTKIKGL EGERENYSRV ASSSSSPKSH VIKQDMDVER SVSDLYKMKH
SVPQSLPQSN YFTTLSNSVV NEPPRSYPSK EISNIYGDKQ SNALAAAAAN PQTLTSFITS
LSKPPPLIKH QPESEGLVGK IPEHLPHQIA SHSVTAFRND CRSPTHLTIS STNTLRSMPA
LHRAPVFHPP IHHSLERKEG SYSSLSPPTL TPVMPVNAGG KIQESQKPPT LIPEPKDSQA
NFKSSSEQSL TEMWRPNNNF SKEKTEWHVE KSSGKLQAAM ASVIVRPSSS TKTDSVPAVQ
LASKDRVSER SSAGAHKTDC LKLAEAGETG RIILPNVNSD SVHTKSEKNF QAVSQGSVPS
SVMSVNTMCN TKTDVITSAA DTTSVSSWGG SEAISSLSNT ILASTSSECT SSKSVSQPVA
QKQECKVSTT APVTLASSKT GSVVQPSSGF SGTTDFIHLK KHKAALAAAQ YKSSNVSETE
PNAIKSQTLS ASLPLDSTVI CSTINKANSV GNGQASQTSQ PNYHTKLKKA WLTRHSEEDK
NTNKMENSGN SVSEIIKPCS VNLIASTSSD IQNSVDSKII VDKYVKDDKV NRRKAKRTYE
SGSESGDSDE SESKSEQRTK RQPKPTYKKK QNDLQKRKGE IEEDLKPNGV LSRSAKEKSK
LKLQSNSNTG IPRSVLKDWR KVKKLKQTGE SFLQDDSCCE IGPNLQKCRE CRLIRSKKGE
EPAHSPVFCR FYYFRRLSFS KNGVVRIDGF SSPDQYDDEA MSLWTHENYE DDELDIETSK
YILDIIGDKF CQLVTSEKTA LSWVKKDAKI AWKRAVRGVR EMCDACEATL FNIHWVCQKC
GFVVCLDCYK AKERKSSRDK ELYAWMKCVK GQPHDHKHLM PTQIIPGSVL TDLLDAMHTL
REKYGIKSHC HCTNKQNLQV GNFPTMNGVS QVLQNVLNHS NKISLCMPES QQQNTPQKSE
KNGGSSPESD VGTDNKLTPP ESQSPLHWLA DLAEQKAREE KKENKELTLE KQIKEEREQD
NSESPNGRTS PLVSQNNEQG STLRDLLTTT AGKLRVGSTD AGIAFAPVYS MGAPSSKSGR
TMPNILDDII ASVVENKIPP SKTSKINVKP ELKEEPEESI ISAVDENNKL YSDIPHSWIC
EKHILWLKDY KNSNNWKLFK ECWKQGQPAV VSGVHKKMNI SLWKAESISL DFGDHQADLL
NCKDSIISNA NVKEFWDGFE EVSKRQKNKS GETVVLKLKD WPSGEDFKTM MPARYEDLLK
SLPLPEYCNP EGKFNLASHL PGFFVRPDLG PRLCSAYGVV AAKDHDIGTT NLHIEVSDVV
NILVYVGIAK GNGILSKAGI LKKFEEEDLD DILRKRLKDS SEIPGALWHI YAGKDVDKIR
EFLQKISKEQ GLEVLPEHDP IRDQSWYVNK KLRQRLLEEY GVRTCTLIQF LGDAIVLPAG
ALHQVQNFHS CIQVTEDFVS PEHLVESFHL TQELRLLKEE INYDDKLQVK NILYHAVKEM
VRALKIHEDE VEDMEEN
//
