ID A0A2K5YH83_MANLE Unreviewed; 673 AA.
AC A0A2K5YH83;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Bromo domain-containing protein {ECO:0000259|PROSITE:PS50014};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000014918.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000014918.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A2K5YH83; -.
DR Ensembl; ENSMLET00000038370.1; ENSMLEP00000014918.1; ENSMLEG00000031562.1.
DR GeneTree; ENSGT00940000153385; -.
DR Proteomes; UP000233140; Unplaced.
DR CDD; cd05497; Bromo_Brdt_I_like; 1.
DR Gene3D; 1.20.1270.220; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 2.
DR InterPro; IPR043508; Bromo_Brdt_I.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR027353; NET_dom.
DR InterPro; IPR038336; NET_sf.
DR PANTHER; PTHR22880:SF240; BROMODOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR22880; FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS; 1.
DR Pfam; PF17035; BET; 1.
DR Pfam; PF00439; Bromodomain; 2.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 2.
DR SUPFAM; SSF47370; Bromodomain; 2.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 2.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 51..115
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 301..365
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 387..432
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 454..562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 604..657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 396..410
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 411..426
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 464..479
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 544..559
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 618..657
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 673 AA; 74095 MW; 430E5E89C0695C80 CRC64;
IALVPALQLT PANPLPQDLP NPKKPEGVTN QLQYLHKVVM EALWKHQFTQ FRQPVDAVKL
APEDYHKIIK QPMDVGTIKR RLENSYYWAT SECMEDLNTM FTNCYIYNKP TDNIVLMAQT
LEKIFLQKVA SMPQEEQELV VTIPNNSHKK GAKLAALQDS VTRAHQVPAI SSVSHTALYT
PPPEIPTMVL NIPHSSVISS SLFKSLHSAE TPLLAVTAAP PAQPLAKKKG IKRKAVTTTP
TPTAILAPGS PASHPGSLEH KVAWLPTCLT YQQQDQSCKK GKLSEQLKHC NGILKELLSK
KHAAYAWPLY KPVDASALGL RNYHDIMRHP MDLSNVKKME NPDYPDAQEF AADVLLMFSN
CYKYNFVAVA RKLQDVFMPD EPLEPGPLPV STAMPLGLAK SSSESSSEES SSESSSEEEE
EEEEENLKEE RAHGLAELQE QLWAVHEQLV GLCQDPISKP KSKREKKEKN KKQKPKKSKK
ASGSGGGSAA LGSPGFGPSG GSGTKLPKKA TKSTPPALPK GYDSEEEEES SPMTYNEKRQ
LSLDINELPG EKLEEIEIGS ETLKPSTLRK LELYILSCIH KKPQRPYTIK KSVGRTKEEL
ALEKKQELEK CPPKKVSEKT ESSSAQQVAV SCLTSSSDSS SFSSSSPSSD TSDSDSGLSM
LLQRTLSSFF MAA
//
