ID A0A2K5YH89_MANLE Unreviewed; 691 AA.
AC A0A2K5YH89;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Bromo domain-containing protein {ECO:0000259|PROSITE:PS50014};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000014907.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000014907.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A2K5YH89; -.
DR STRING; 9568.ENSMLEP00000014907; -.
DR Ensembl; ENSMLET00000038359.1; ENSMLEP00000014907.1; ENSMLEG00000031562.1.
DR GeneTree; ENSGT00940000153385; -.
DR OMA; SEDSETX; -.
DR Proteomes; UP000233140; Unplaced.
DR CDD; cd05497; Bromo_Brdt_I_like; 1.
DR Gene3D; 1.20.1270.220; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 2.
DR InterPro; IPR043508; Bromo_Brdt_I.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR027353; NET_dom.
DR InterPro; IPR038336; NET_sf.
DR PANTHER; PTHR22880:SF240; BROMODOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR22880; FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS; 1.
DR Pfam; PF17035; BET; 1.
DR Pfam; PF00439; Bromodomain; 2.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 2.
DR SUPFAM; SSF47370; Bromodomain; 2.
DR PROSITE; PS50014; BROMODOMAIN_2; 2.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Reference proteome {ECO:0000313|Proteomes:UP000233140}.
FT DOMAIN 78..142
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 328..392
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 414..459
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 481..568
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 642..691
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..437
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 438..453
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..506
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 691 AA; 76233 MW; 0D8D296CCE29BFC3 CRC64;
MLQNTAPHNK LPGEEGCWGW AQKQYHTIAL VPALQLTPAN PLPQDLPNPK KPEGVTNQLQ
YLHKVVMEAL WKHQFTQFRQ PVDAVKLAPE DYHKIIKQPM DVGTIKRRLE NSYYWATSEC
MEDLNTMFTN CYIYNKPTDN IVLMAQTLEK IFLQKVASMP QEEQELVVTI PNNSHKKGAK
LAALQDSVTR AHQVPAISSV SHTALYTPPP EIPTMVLNIP HSSVISSSLF KSLHSAETPL
LAVTAAPPAQ PLAKKKGIKR KAVTTTPTPT AILAPGSPAS HPGSLEHKVA WLPTCLTYQQ
QDQSCKKGKL SEQLKHCNGI LKELLSKKHA AYAWPLYKPV DASALGLRNY HDIMRHPMDL
SNVKKMENPD YPDAQEFAAD VLLMFSNCYK YNFVAVARKL QDVFMPDEPL EPGPLPVSTA
MPLGLAKSSS ESSSEESSSE SSSEEEEEEE EENLKEERAH GLAELQEQLW AVHEQLVGLC
QDPISKPKSK REKKEKNKKQ KPKKSKKASG SGGGSAALGS PGFGPSGGSG TKLPKKATKS
TPPALPKGYD SEEEEESSPM TYNEKRQLSL DINELPGEKL EEIEIGSETL KPSTLRKLEL
YILSCIHKKP QRPYTIKKSV GRTKEELALE KKQELEKWLQ DVSGQLNSPK NEKTESSSAQ
QVAVSCLTSS SDSSSFSSSS PSSDTSDSDS G
//
