ID   A0A2K5YJK9_MANLE        Unreviewed;       131 AA.
AC   A0A2K5YJK9;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=MDM4 regulator of p53 {ECO:0000313|Ensembl:ENSMLEP00000015746.1};
GN   Name=MDM4 {ECO:0000313|Ensembl:ENSMLEP00000015746.1};
OS   Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Mandrillus.
OX   NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000015746.1, ECO:0000313|Proteomes:UP000233140};
RN   [1] {ECO:0000313|Ensembl:ENSMLEP00000015746.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K5YJK9; -.
DR   Ensembl; ENSMLET00000039208.1; ENSMLEP00000015746.1; ENSMLEG00000032041.1.
DR   GeneTree; ENSGT00530000063539; -.
DR   Proteomes; UP000233140; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR   CDD; cd17673; MDM4; 1.
DR   Gene3D; 1.10.245.10; SWIB/MDM2 domain; 1.
DR   InterPro; IPR016495; p53_neg-reg_MDM_2/4.
DR   InterPro; IPR036885; SWIB_MDM2_dom_sf.
DR   InterPro; IPR003121; SWIB_MDM2_domain.
DR   PANTHER; PTHR12183; MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1; 1.
DR   PANTHER; PTHR12183:SF37; PROTEIN MDM4; 1.
DR   Pfam; PF02201; SWIB; 1.
DR   PIRSF; PIRSF006748; p53_MDM_2/4; 1.
DR   SUPFAM; SSF47592; SWIB/MDM2 domain; 1.
DR   PROSITE; PS51925; SWIB_MDM2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          25..108
FT                   /note="DM2"
FT                   /evidence="ECO:0000259|PROSITE:PS51925"
SQ   SEQUENCE   131 AA;  14581 MW;  9C489F66BE24B295 CRC64;
     MTSFSTSAQC STSDSACRIS PGQINQVRPK LPLLKILHAA GAQGEMFTVK EVMHYLGQYI
     MVKQLYDQQE QHMVYCGGDL LGELLGRQSF SVKDPSPLYD MLRKNLVTLA TATTEMGHLF
     CRISHVLELA D
//