ID   A0A2K5YM17_MANLE        Unreviewed;       653 AA.
AC   A0A2K5YM17;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Stromal interaction molecule 1 {ECO:0000313|Ensembl:ENSMLEP00000016596.1};
GN   Name=STIM1 {ECO:0000313|Ensembl:ENSMLEP00000016596.1};
OS   Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Mandrillus.
OX   NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000016596.1, ECO:0000313|Proteomes:UP000233140};
RN   [1] {ECO:0000313|Ensembl:ENSMLEP00000016596.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC       pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR   AlphaFoldDB; A0A2K5YM17; -.
DR   Ensembl; ENSMLET00000040067.1; ENSMLEP00000016596.1; ENSMLEG00000032366.1.
DR   GeneTree; ENSGT00390000000214; -.
DR   Proteomes; UP000233140; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005246; F:calcium channel regulator activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0051049; P:regulation of transport; IEA:UniProt.
DR   CDD; cd09573; SAM_STIM1; 1.
DR   CDD; cd11722; SOAR; 1.
DR   Gene3D; 1.10.238.180; -; 1.
DR   Gene3D; 1.10.287.3550; -; 1.
DR   Gene3D; 1.20.5.340; -; 1.
DR   Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR   InterPro; IPR001660; SAM.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR032393; SOAR.
DR   InterPro; IPR037608; STIM.
DR   InterPro; IPR037609; STIM1_SAM.
DR   PANTHER; PTHR15136:SF9; STROMAL INTERACTION MOLECULE 1; 1.
DR   PANTHER; PTHR15136; STROMAL INTERACTION MOLECULE HOMOLOG; 1.
DR   Pfam; PF07647; SAM_2; 1.
DR   Pfam; PF16533; SOAR; 1.
DR   SMART; SM00454; SAM; 1.
DR   SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR   PROSITE; PS50105; SAM_DOMAIN; 1.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Calcium transport {ECO:0000256|ARBA:ARBA00022568};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        183..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          101..159
FT                   /note="SAM"
FT                   /evidence="ECO:0000259|PROSITE:PS50105"
FT   REGION          459..511
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          564..653
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          220..310
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        459..487
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        575..589
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   653 AA;  73872 MW;  1CCD7F54954410D8 CRC64;
     AGRGGACLSH HCATTLFCRI DKPLCHSEDE KLSFEAVRNI HKLMDDDANG DVDVEESDEF
     LREDLNYHDP TVKHSTFHGE DKLISVEDLW KAWKSSEVYN WTVDEVVQWL ITYVELPQYE
     ETFRKLQLSG HAMPRLAVTN TTMTGTVLKM TDRSHRQKLQ LKALDTVLFG PPLLTRHNHL
     KDFMLVVSIV IGVGGCWFAY IQNRYSKEHM KKMMKDLEGL HRAEQSLHDL QERLHKAQEE
     HRTVEVEKVH LEKKLRDEIN LAKQEAQRLK ELREGTENER SRQKYAEEEL EQVREALRKA
     EKELESHSSW YAPEALQKWL QLTHEVEVQY YNIKKQNAEK QLLVAKEGAE KIKKKRNTLF
     GTFHVAHSSS LDDVDHKILT AKQALSEVTA ALRERLHRWQ QIEILCGFQI VNNPGIHSLV
     AALNIDPSWM GSTRPNPAHF IMTDDVDDMD EEIVSPLSMQ SPSLQSSVRQ RLTEPQHGLG
     SQRDLTHSDS ESSLHMSDRQ RVAPKPPQMS RAADEALNAM TSNGSHRLIE GVHPGSLMEK
     LPDSPALAKA LLALNHGLDK AHSLMELSPS APPGGSPHLD SSRSHSPSSP DPDTPSPVGD
     SRALQASRNT RIPHLAGKKA VAEEDNGSIG EETDSSPGRK KFPLKIFKKP LKK
//