ID A0A2K5YUG0_MANLE Unreviewed; 553 AA.
AC A0A2K5YUG0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=DAB adaptor protein 1 {ECO:0000313|Ensembl:ENSMLEP00000019202.1};
GN Name=DAB1 {ECO:0000313|Ensembl:ENSMLEP00000019202.1};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000019202.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000019202.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_011829242.1; XM_011973852.1.
DR AlphaFoldDB; A0A2K5YUG0; -.
DR Ensembl; ENSMLET00000042691.1; ENSMLEP00000019202.1; ENSMLEG00000033725.1.
DR GeneID; 105534916; -.
DR CTD; 1600; -.
DR GeneTree; ENSGT00940000158038; -.
DR OrthoDB; 2913989at2759; -.
DR Proteomes; UP000233140; Unplaced.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR CDD; cd01215; PTB_Dab; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR048559; DAB1/2_SBM.
DR InterPro; IPR048561; Dab_PTB.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006020; PTB/PI_dom.
DR PANTHER; PTHR47695:SF4; DISABLED HOMOLOG 1; 1.
DR PANTHER; PTHR47695; PID DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF21792; DAB2_SBM; 1.
DR Pfam; PF00640; PID; 1.
DR SMART; SM00462; PTB; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS01179; PID; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Reference proteome {ECO:0000313|Proteomes:UP000233140}.
FT DOMAIN 37..169
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 382..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 416..435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 467..553
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..26
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..402
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 520..553
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 553 AA; 59612 MW; 4373CA8F4430A184 CRC64;
MSTETELQVA VKTSAKKDSR KKGQDRSEAT LIKRFKGEGV RYKAKLIGID EVSAARGDKL
CQDSMMKLKG VVAGARSKGE HKQKIFLTIS FGGIKIFDEK TGALQHHHAV HEISYIAKDI
TDHRAFGYVC GKEGNHRFVA IKTAQAAEPV ILDLRDLFQL IYELKQREEL EKKAQKDKQC
EQAVYQVPTS QKKEGVYDVP KSQPVSNGYS FEDFEERFAA ATPNRNLPTD FDEIFEATKA
VTQLELFGDM STPPDITSPP TPATPGDAFI PSSSQTLPAS ADVFGSVPFS TAAVPSGYVA
MGAVLPSFWG QQPLVQQQMV MGAQPPVAQV MPGAQPIAWG QPGLFPATQQ PWPTVAGQFP
PAAFMPTQTV MPLPAAMFQG PLTPLATVPG TSDSTRSSPQ TDKPRQKMGK ETFKDFQMAQ
PPPVPSRKPD QPSLTCTSEA FSSYFNKVGV AQDTDDCDDF DISQLNLTPV TSTTPSTNSP
PTPAPRQSSP SKSSASHASD PTTDDIFEEG FESPSKSEEQ EAPDGSQASS NSDPFGEPSG
EPSGDNISPQ AGS
//
