ID   A0A2K5YXP1_MANLE        Unreviewed;       631 AA.
AC   A0A2K5YXP1;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Interleukin 17 receptor D {ECO:0000313|Ensembl:ENSMLEP00000020323.1};
GN   Name=IL17RD {ECO:0000313|Ensembl:ENSMLEP00000020323.1};
OS   Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Mandrillus.
OX   NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000020323.1, ECO:0000313|Proteomes:UP000233140};
RN   [1] {ECO:0000313|Ensembl:ENSMLEP00000020323.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC       pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR   AlphaFoldDB; A0A2K5YXP1; -.
DR   STRING; 9568.ENSMLEP00000020323; -.
DR   Ensembl; ENSMLET00000043819.1; ENSMLEP00000020323.1; ENSMLEG00000034371.1.
DR   GeneTree; ENSGT00940000156669; -.
DR   OMA; YYYLHYK; -.
DR   Proteomes; UP000233140; Unplaced.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0030368; F:interleukin-17 receptor activity; IEA:InterPro.
DR   GO; GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IEA:Ensembl.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   Gene3D; 3.40.50.11530; -; 1.
DR   InterPro; IPR039465; IL-17_rcpt-like.
DR   InterPro; IPR031951; IL17R_D_N.
DR   InterPro; IPR013568; SEFIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR15583; INTERLEUKIN-17 RECEPTOR; 1.
DR   PANTHER; PTHR15583:SF14; INTERLEUKIN-17 RECEPTOR D; 1.
DR   Pfam; PF16742; IL17R_D_N; 1.
DR   Pfam; PF08357; SEFIR; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS51534; SEFIR; 1.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          247..401
FT                   /note="SEFIR"
FT                   /evidence="ECO:0000259|PROSITE:PS51534"
FT   REGION          542..608
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        557..594
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   631 AA;  70228 MW;  7EEEFFFA2DBC0CD1 CRC64;
     GVGPASRNSG LYNITFKYDN CTTYLNPVGK HVIADAQNIT ISQYACHDQV AVTILWSPGA
     LGIEFLKGFR VILEELKSEG RQCQQLILKD PKQLNSSFKR TGMESQPFLN MKFETDYFVK
     VVPFPSIKNE SNYHPFFFRT REQNTETTSC LLQNVSPGDY IIELMDDTNT TRKVMHYALK
     PVHSPWAGPI RAVAITVPLV VISAFATLFT VMCRKKQQEN IYSHLDEESS ESSTYTAVLP
     RERLRPRPKV FLCYSSKDGQ NHMNVVQCFA YFLQDFCGCE VALDLWEDFS LCREGQREWV
     IQKIHESQFI IVVCSKGMKY FVDKKNYKHK GGGRGSGKGE LFLVAVSAIA EKLRQAKQSS
     SAALSKFIAV YFDYSCEGDV PGVLDLSTKY KLMDNLPQLC SHLHSRDHGL QEPGQHARQG
     SRRNYFRSKS GRSLYVAICN MHQFIDEEPD WFEKQFVPFH APPLRYREPV LEKFDSGLVL
     NDVMCKPGPE SDFCLKVEAA VLGATGPADS QHESQHGGLD QDAEARPALD GSAALQPLLH
     TVKAGSPSDM PRDSGIYDSS VPSSELSLPL MEGLSTDQTE TSSLTESVSS SSGLGEEEPP
     ALPSKLLSSG ACKADLGCRS YTDELHAVAP L
//