ID A0A2K5YYD4_MANLE Unreviewed; 215 AA.
AC A0A2K5YYD4;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=FA core complex associated protein 24 {ECO:0000313|Ensembl:ENSMLEP00000020550.1};
GN Name=FAAP24 {ECO:0000313|Ensembl:ENSMLEP00000020550.1};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000020550.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000020550.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_011850635.1; XM_011995245.1.
DR RefSeq; XP_011850636.1; XM_011995246.1.
DR AlphaFoldDB; A0A2K5YYD4; -.
DR SMR; A0A2K5YYD4; -.
DR STRING; 9568.ENSMLEP00000020550; -.
DR Ensembl; ENSMLET00000044048.1; ENSMLEP00000020550.1; ENSMLEG00000034497.1.
DR GeneID; 105550346; -.
DR KEGG; mleu:105550346; -.
DR CTD; 91442; -.
DR GeneTree; ENSGT00390000009456; -.
DR OMA; GPVHVPF; -.
DR OrthoDB; 2906428at2759; -.
DR Proteomes; UP000233140; Unplaced.
DR GO; GO:0000785; C:chromatin; IEA:Ensembl.
DR GO; GO:0071821; C:FANCM-MHF complex; IEA:Ensembl.
DR GO; GO:0043240; C:Fanconi anaemia nuclear complex; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR GO; GO:0036297; P:interstrand cross-link repair; IEA:Ensembl.
DR CDD; cd20076; XPF_nuclease_FAAP24; 1.
DR Gene3D; 3.40.50.10130; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR InterPro; IPR041663; DisA/LigA_HHH.
DR InterPro; IPR026985; FAAP24.
DR InterPro; IPR040646; PND.
DR InterPro; IPR010994; RuvA_2-like.
DR PANTHER; PTHR31786; FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 24; 1.
DR PANTHER; PTHR31786:SF2; FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 24; 1.
DR Pfam; PF12826; HHH_2; 1.
DR Pfam; PF17949; PND; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Reference proteome {ECO:0000313|Proteomes:UP000233140}.
FT DOMAIN 12..134
FT /note="Fanconi anemia core complex-associated protein 24
FT pseudonuclease"
FT /evidence="ECO:0000259|Pfam:PF17949"
FT DOMAIN 166..214
FT /note="DisA/LigA helix-hairpin-helix motif"
FT /evidence="ECO:0000259|Pfam:PF12826"
SQ SEQUENCE 215 AA; 24038 MW; A39B5A2B5204800A CRC64;
MEKKPPDDTG PVHVPLGHIV ANEKWRGSQL AQEMQGKIKL IFEDGLTPDF YLSNRCCVLY
VTEADLVAGN GYRKRLVRVR NSGNLQGIVV VEKTRMSEQY FPALQKFTVL DLGMVLLPVA
SQMEASCLVI QLVQEQTKEP SKNPLLRKKR ALLLSEPSLL RTVQQIPGVG KVKAPLLLQK
FPSIQQLSNA SIRELEQVVG QAVAKQIHAF FTQPR
//
