ID A0A2K5Z091_MANLE Unreviewed; 132 AA.
AC A0A2K5Z091;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Myelin P2 protein {ECO:0000256|ARBA:ARBA00018567};
GN Name=PMP2 {ECO:0000313|Ensembl:ENSMLEP00000021215.1};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000021215.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000021215.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: May play a role in lipid transport protein in Schwann cells.
CC May bind cholesterol. {ECO:0000256|ARBA:ARBA00025662}.
CC -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the calycin superfamily. Fatty-acid binding
CC protein (FABP) family. {ECO:0000256|ARBA:ARBA00008390,
CC ECO:0000256|RuleBase:RU003696}.
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DR RefSeq; XP_011845160.1; XM_011989770.1.
DR AlphaFoldDB; A0A2K5Z091; -.
DR STRING; 9568.ENSMLEP00000021215; -.
DR Ensembl; ENSMLET00000044715.1; ENSMLEP00000021215.1; ENSMLEG00000034823.1.
DR GeneID; 105546535; -.
DR KEGG; mleu:105546535; -.
DR CTD; 5375; -.
DR GeneTree; ENSGT00940000160445; -.
DR OMA; YITIRTE; -.
DR OrthoDB; 46617at2759; -.
DR Proteomes; UP000233140; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0043209; C:myelin sheath; IEA:InterPro.
DR GO; GO:0015485; F:cholesterol binding; IEA:Ensembl.
DR GO; GO:0005504; F:fatty acid binding; IEA:Ensembl.
DR GO; GO:0061024; P:membrane organization; IEA:Ensembl.
DR CDD; cd19469; FABP8; 1.
DR Gene3D; 2.40.128.20; -; 1.
DR InterPro; IPR012674; Calycin.
DR InterPro; IPR000463; Fatty_acid-bd.
DR InterPro; IPR031259; ILBP.
DR InterPro; IPR000566; Lipocln_cytosolic_FA-bd_dom.
DR InterPro; IPR031256; Myelin_P2.
DR PANTHER; PTHR11955; FATTY ACID BINDING PROTEIN; 1.
DR PANTHER; PTHR11955:SF64; MYELIN P2 PROTEIN; 1.
DR Pfam; PF00061; Lipocalin; 1.
DR PRINTS; PR00178; FATTYACIDBP.
DR SUPFAM; SSF50814; Lipocalins; 1.
DR PROSITE; PS00214; FABP; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003696}.
FT DOMAIN 7..24
FT /note="Cytosolic fatty-acid binding proteins"
FT /evidence="ECO:0000259|PROSITE:PS00214"
SQ SEQUENCE 132 AA; 14907 MW; D0E60B98DFEE3364 CRC64;
MSNKFLGTWK LVSSENFDDY MKALGVGLAT RKLGNLAKPT VIISKKGDIL TIRTESTFKN
TEISFKLGQE FEETTADNRK AKSIVTLQRG SLNQVQRWDG KETTIKRKLV NGKMVVECKM
KGVVCTRIYE KV
//
