ID A0A2K5Z1U4_MANLE Unreviewed; 1366 AA.
AC A0A2K5Z1U4;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Protocadherin gamma subfamily B, 1 {ECO:0000313|Ensembl:ENSMLEP00000021779.1};
GN Name=PCDHGB1 {ECO:0000313|Ensembl:ENSMLEP00000021779.1};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000021779.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000021779.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR Ensembl; ENSMLET00000045283.1; ENSMLEP00000021779.1; ENSMLEG00000035089.1.
DR GeneTree; ENSGT00940000163837; -.
DR OMA; THEYNIT; -.
DR Proteomes; UP000233140; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR GO; GO:0007399; P:nervous system development; IEA:UniProt.
DR CDD; cd11304; Cadherin_repeat; 11.
DR Gene3D; 2.60.40.60; Cadherins; 11.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR032455; Cadherin_C.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF144; PROTOCADHERIN GAMMA-B2; 1.
DR Pfam; PF00028; Cadherin; 9.
DR Pfam; PF08266; Cadherin_2; 2.
DR Pfam; PF16492; Cadherin_C_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 11.
DR SUPFAM; SSF49313; Cadherin-like; 11.
DR PROSITE; PS00232; CADHERIN_1; 6.
DR PROSITE; PS50268; CADHERIN_2; 11.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..1366
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014358880"
FT TRANSMEM 1242..1265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..130
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 131..239
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 240..343
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 344..448
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 449..558
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 574..685
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 686..794
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 795..899
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 908..1004
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1005..1114
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1130..1227
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
SQ SEQUENCE 1366 AA; 148827 MW; 25FD90A5FF32C695 CRC64;
MQRVREAETM KSQVLFPFLL SLFCGAISQQ IRYTIPEELA NGSRVGNLAK DLGLSVQELP
TRKLRVSAED YFNVSLESGD LLVNGRIDRE KICGRKLECA LEFETVSENP MNVFHVVVVI
QDINDNAPRF VAKGINLEIC ESALPGVKFS LDSAQDADVD GNSLKIYTIN PNQYFSLSTK
ESPDGSKYPE LLLEKPLDRE HQSSHRLILT AMDGGDPPLS GTTHISIRVT DANDNAPMFS
QDVYRVSLQE NVPWGTSVLR VMATDQDEGI NAEITYAFLN SPISTSLFNL NPNTGDITTN
GTLDFEETSR YVLGVEAKDG GVHTAHCNVQ IEIVDENDNA PEVTFMSFSN QIPEDSDLGT
VIALIKVRDK DSGQNGMVTC SIQEDVPFKL ESTSKNFYKM VIGGALNREQ TADYNITIIA
TDKGKPSLSS RTSITLHISD INDNAPVFHQ ASYVVHVAEN NPPGASIAQV SASDPDLGPN
GSVSYSILAS DLEPQELLSY VSVSAQSGVV FAQRAFDHEQ LRAFELTLQA CDQGSPALSA
NVSLRVLVGD LNDNAPRVLY PALGSDGSAL FDMVPRAAEP GYLVTKVVAV DADSGHNAWL
SYHVLQASDV RDLPARKLRV SAEKEYFTVN PESGDLIVGD KIDREQICGK QPLCVLDFDT
VAENPLNIFH IAVIVQDIND NTPLFKQSKI HLKIGESTKP GTTFPLDPAL DSDVGPNSLQ
RYHLNDNEYF DLAEKRTPDG RKYPELILKH SLDREEHSFH QLVLTAVDGG DPPQSGTTQI
RIQVTDANDN PPVFSQDVYR VTLREDVPPG FFVLQVTATD RDEGINAEIT YSFHNVDEQV
KRFFNLNEKT GEITTKDDLD FEIASSYTLS IEAKDPGDLA AHCSIQVEIL DENDCAPEVI
VTSVFTPLPE DSPPGTVIAL IKTRDRDSGE NGEVYCQVLG NAKFILKSSS KNYYKLMTDG
ALDREEIPEY NLTITATDGG KPPLSSSIIV TLHISDVNDN APLFQQTCYM VHVAENNPPG
ASIAQISASD PDLGPNGQVS YSILASDLEP RKILSYVSVS AQSGVVFAQR AFDHEQLRAF
ELTLQATDQG SPALSANVSL RVLVGDLNDN VPLVLYPALG PDGSALFDMV PRAAEPGYLV
TKVVAVDADS GHNAWLSYHV LQASEPGLFS LGLRTGEVRT ARALGERDAA RQRLLVAVRD
GGQPPLSATA TLHLIFADSL QEVLPDLSGS PEPSDPQTEL QFYLVVALAL ISVLFLLAVI
LAIALRLRRS SSLNTEGYFQ TGLCSKSGPE VPPNHSEGTL PYSYNLCVAS HSAKTEFNFL
NLTPEMTPPQ DLLCDDPSMI VCASNEDHKV AYDPSLSSHV SFCKSS
//
