ID A0A2K5Z4C0_MANLE Unreviewed; 223 AA.
AC A0A2K5Z4C0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta {ECO:0000313|Ensembl:ENSMLEP00000022605.1};
GN Name=YWHAH {ECO:0000313|Ensembl:ENSMLEP00000022605.1};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000022605.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000022605.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the 14-3-3 family.
CC {ECO:0000256|ARBA:ARBA00006141, ECO:0000256|RuleBase:RU003466}.
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DR AlphaFoldDB; A0A2K5Z4C0; -.
DR STRING; 9568.ENSMLEP00000022605; -.
DR Ensembl; ENSMLET00000046117.1; ENSMLEP00000022605.1; ENSMLEG00000035520.1.
DR GeneTree; ENSGT01090000260061; -.
DR OMA; IEQKTMS; -.
DR Proteomes; UP000233140; Unplaced.
DR GO; GO:0150048; C:cerebellar granule cell to Purkinje cell synapse; IEA:Ensembl.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0098793; C:presynapse; IEA:Ensembl.
DR GO; GO:0003779; F:actin binding; IEA:Ensembl.
DR GO; GO:0019899; F:enzyme binding; IEA:Ensembl.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0035259; F:nuclear glucocorticoid receptor binding; IEA:Ensembl.
DR GO; GO:0019904; F:protein domain specific binding; IEA:Ensembl.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:Ensembl.
DR GO; GO:0017080; F:sodium channel regulator activity; IEA:Ensembl.
DR GO; GO:0044325; F:transmembrane transporter binding; IEA:Ensembl.
DR GO; GO:0006713; P:glucocorticoid catabolic process; IEA:Ensembl.
DR GO; GO:0042921; P:glucocorticoid receptor signaling pathway; IEA:Ensembl.
DR GO; GO:0006886; P:intracellular protein transport; IEA:Ensembl.
DR GO; GO:0086010; P:membrane depolarization during action potential; IEA:Ensembl.
DR GO; GO:0050774; P:negative regulation of dendrite morphogenesis; IEA:Ensembl.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:Ensembl.
DR GO; GO:0099171; P:presynaptic modulation of chemical synaptic transmission; IEA:Ensembl.
DR GO; GO:0002028; P:regulation of sodium ion transport; IEA:Ensembl.
DR Gene3D; 1.20.190.20; 14-3-3 domain; 1.
DR InterPro; IPR000308; 14-3-3.
DR InterPro; IPR023409; 14-3-3_CS.
DR InterPro; IPR036815; 14-3-3_dom_sf.
DR InterPro; IPR023410; 14-3-3_domain.
DR PANTHER; PTHR18860; 14-3-3 PROTEIN; 1.
DR PANTHER; PTHR18860:SF16; 14-3-3 PROTEIN ETA; 1.
DR Pfam; PF00244; 14-3-3; 1.
DR PIRSF; PIRSF000868; 14-3-3; 1.
DR PRINTS; PR00305; 1433ZETA.
DR SMART; SM00101; 14_3_3; 1.
DR SUPFAM; SSF48445; 14-3-3 protein; 1.
DR PROSITE; PS00796; 1433_1; 1.
DR PROSITE; PS00797; 1433_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000233140}.
FT DOMAIN 1..223
FT /note="14-3-3"
FT /evidence="ECO:0000259|SMART:SM00101"
FT SITE 34
FT /note="Interaction with phosphoserine on interacting
FT protein"
FT /evidence="ECO:0000256|PIRSR:PIRSR000868-1"
FT SITE 109
FT /note="Interaction with phosphoserine on interacting
FT protein"
FT /evidence="ECO:0000256|PIRSR:PIRSR000868-1"
SQ SEQUENCE 223 AA; 25547 MW; C0014CE33CC0B93D CRC64;
SCTNMKVTEL NEPLSNEDRN LLSVAYKNVV GARRSSWRVI SSIEQKTMAD GNEKKLEKVK
AYREKIEKEL ETVCNDVLSL LDKFLIKNCN DFQYESKVFY LKMKGDYYRY LAEVASGEKK
NSVVEASEAA YKEAFEISKE QMQPTHPIRL GLALNFSVFY YEIQNAPEQA CLLAKQAFDD
AIAELDTLNE DSYKDSTLIM QLLRDNLTLW TSDQQDEEAG EGN
//
