ID   A0A2K5Z8U7_MANLE        Unreviewed;       909 AA.
AC   A0A2K5Z8U7;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Myocardin related transcription factor A {ECO:0000313|Ensembl:ENSMLEP00000024249.1};
GN   Name=MRTFA {ECO:0000313|Ensembl:ENSMLEP00000024249.1};
OS   Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Mandrillus.
OX   NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000024249.1, ECO:0000313|Proteomes:UP000233140};
RN   [1] {ECO:0000313|Ensembl:ENSMLEP00000024249.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K5Z8U7; -.
DR   Ensembl; ENSMLET00000047770.1; ENSMLEP00000024249.1; ENSMLEG00000036191.1.
DR   GeneTree; ENSGT00950000182979; -.
DR   Proteomes; UP000233140; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:UniProt.
DR   Gene3D; 6.10.150.10; -; 1.
DR   Gene3D; 1.10.720.30; SAP domain; 1.
DR   InterPro; IPR043451; Myocardin-like.
DR   InterPro; IPR004018; RPEL_repeat.
DR   InterPro; IPR003034; SAP_dom.
DR   InterPro; IPR036361; SAP_dom_sf.
DR   PANTHER; PTHR22793:SF6; MYOCARDIN-RELATED TRANSCRIPTION FACTOR A; 1.
DR   PANTHER; PTHR22793; MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED; 1.
DR   Pfam; PF02755; RPEL; 1.
DR   Pfam; PF02037; SAP; 1.
DR   SMART; SM00707; RPEL; 2.
DR   SMART; SM00513; SAP; 1.
DR   SUPFAM; SSF68906; SAP domain; 1.
DR   PROSITE; PS51073; RPEL; 2.
DR   PROSITE; PS50800; SAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   REPEAT          1..23
FT                   /note="RPEL"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT   REPEAT          42..67
FT                   /note="RPEL"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT   DOMAIN          321..355
FT                   /note="SAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50800"
FT   REGION          84..233
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          264..318
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          419..445
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          531..569
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          652..724
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          741..794
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        84..114
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        123..139
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        152..166
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        167..191
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        280..314
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        652..676
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        710..724
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        774..788
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   909 AA;  96161 MW;  F06F6215450D412F CRC64;
     KRKIRSRPER SELVRMHILE ETSAEPSLQA KQLKLKRARL ADDLNEKIAQ RPGPMELVEK
     NILPVESSLK EAIIVGQVNY PKVADSSSFD EDSSDALSPE QPASHESQGS VPSPLEARVS
     EPLPSATSAS PTQVVSQLPM GPDSGEMLFL AEQPPLPPPP LLPPSLTNGT TVPTAKPTPT
     LIKQSQPKSA SEKSQRSKKA KELKPKVKKL KYHQYIPPDQ KQDRGAPPMD SSYAKILQQQ
     QLFLQLQILN QQQQQHHNYQ AILPAPPKSA GEALGSSGTP PVRSLPTTSS SSSSGAPGPC
     GLARQNSTSL TGKPGALPAN LDDMKVAELK QELKLRSLPV SGTKTELIER LRAYQDQIGP
     VPGAPKAPAT TSILHKAGEV VVAFPAARLS TGPALVAAGL APTEVVVATV TSNGVVKFGS
     TGSTPPVSPT PSERSLLSTG DENSTPGDTF GEMVTSPLTQ LTLQASPLQI LVKEEGPRAG
     SCCLSPGGRA ELEGRDKDQM LQEKDKQIEE LTRMLRQKQQ LVERLRLQLE QEKRAQQPAP
     TPVPTPAPLG MPVKQENSFS SCQLSRQPLG PAHPFSPSLA APTTNHVDPC AAAPGPPSVV
     VKQEAVQPEP EPVPAPQLLL GPQGPGLIKG VAPPTLITDS TGTHLVLTVT NKNADSPGLS
     SGSPQQPSSQ PGSPVPAASA QMDLEHPLQP VFGTPTSLLK KEPPGYEEAM SQQPKQQENG
     SSSQQMDDLF DILIQSGEIS ADFKEPPSLP GKEKPSPKTA CGSPLAAQPS PSAELPQAAP
     PPPGSPSLPG RLEDFLESST GLPLLTSGHE GPEPLSLIDD LHSQMLSSTA ILDHPPSPMD
     TSELHFAPEP SSTMGLDLAD GHLDSMDWLE LSSGGPVLSL APLSTTAPSL FSTDFLDGHD
     LQLHWDSCL
//