ID A0A2K5Z8X6_MANLE Unreviewed; 125 AA.
AC A0A2K5Z8X6;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=C-C motif chemokine {ECO:0000256|RuleBase:RU361150};
GN Name=CCL23 {ECO:0000313|Ensembl:ENSMLEP00000024268.1};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000024268.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000024268.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU361150}.
CC -!- SIMILARITY: Belongs to the intercrine beta (chemokine CC) family.
CC {ECO:0000256|ARBA:ARBA00010868, ECO:0000256|RuleBase:RU361150}.
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DR AlphaFoldDB; A0A2K5Z8X6; -.
DR STRING; 9568.ENSMLEP00000024268; -.
DR Ensembl; ENSMLET00000047790.1; ENSMLEP00000024268.1; ENSMLEG00000036290.1.
DR GeneTree; ENSGT01100000263482; -.
DR OMA; TIRCSAI; -.
DR Proteomes; UP000233140; Unplaced.
DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR GO; GO:0031726; F:CCR1 chemokine receptor binding; IEA:Ensembl.
DR GO; GO:0008009; F:chemokine activity; IEA:Ensembl.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR CDD; cd00272; Chemokine_CC; 1.
DR Gene3D; 2.40.50.40; -; 1.
DR InterPro; IPR039809; Chemokine_b/g/d.
DR InterPro; IPR000827; Chemokine_CC_CS.
DR InterPro; IPR001811; Chemokine_IL8-like_dom.
DR InterPro; IPR036048; Interleukin_8-like_sf.
DR PANTHER; PTHR12015:SF157; C-C MOTIF CHEMOKINE 23; 1.
DR PANTHER; PTHR12015; SMALL INDUCIBLE CYTOKINE A; 1.
DR Pfam; PF00048; IL8; 1.
DR SMART; SM00199; SCY; 1.
DR SUPFAM; SSF54117; Interleukin 8-like chemokines; 1.
DR PROSITE; PS00472; SMALL_CYTOKINES_CC; 1.
PE 3: Inferred from homology;
KW Chemotaxis {ECO:0000256|ARBA:ARBA00022500, ECO:0000256|RuleBase:RU361150};
KW Cytokine {ECO:0000256|ARBA:ARBA00022514, ECO:0000256|RuleBase:RU361150};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Inflammatory response {ECO:0000256|ARBA:ARBA00023198};
KW Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW Secreted {ECO:0000256|ARBA:ARBA00022525, ECO:0000256|RuleBase:RU361150};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU361150}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|RuleBase:RU361150"
FT CHAIN 22..125
FT /note="C-C motif chemokine"
FT /evidence="ECO:0000256|RuleBase:RU361150"
FT /id="PRO_5014207889"
FT DOMAIN 56..114
FT /note="Chemokine interleukin-8-like"
FT /evidence="ECO:0000259|SMART:SM00199"
SQ SEQUENCE 125 AA; 13682 MW; 3F42E702252783DE CRC64;
MKVSVAVLSC LMLVTALGSQ AQVTNGESSE DTLPSCHYSP SQTWSWYSFK SFHAINADCC
TSYIPGSIPC SLLESYLETS SKCPKPGVIF LTKNGRRLCV SPSNKQVLAC RIMLKLATRI
KARKN
//
