ID   A0A2K5ZAT6_MANLE        Unreviewed;       561 AA.
AC   A0A2K5ZAT6;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155};
DE            EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};
GN   Name=CHST15 {ECO:0000313|Ensembl:ENSMLEP00000024875.1};
OS   Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Mandrillus.
OX   NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000024875.1, ECO:0000313|Proteomes:UP000233140};
RN   [1] {ECO:0000313|Ensembl:ENSMLEP00000024875.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the sulfotransferase 1 family.
CC       {ECO:0000256|RuleBase:RU361155}.
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DR   RefSeq; XP_011841804.1; XM_011986414.1.
DR   AlphaFoldDB; A0A2K5ZAT6; -.
DR   STRING; 9568.ENSMLEP00000024875; -.
DR   Ensembl; ENSMLET00000048401.1; ENSMLEP00000024875.1; ENSMLEG00000036608.1.
DR   GeneID; 105544130; -.
DR   KEGG; mleu:105544130; -.
DR   CTD; 51363; -.
DR   GeneTree; ENSGT00390000004719; -.
DR   OMA; HVDSKQM; -.
DR   OrthoDB; 3939141at2759; -.
DR   Proteomes; UP000233140; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0050656; F:3'-phosphoadenosine 5'-phosphosulfate binding; IEA:Ensembl.
DR   GO; GO:0050659; F:N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity; IEA:Ensembl.
DR   GO; GO:0019319; P:hexose biosynthetic process; IEA:Ensembl.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000863; Sulfotransferase_dom.
DR   PANTHER; PTHR15723; CARBOHYDRATE SULFOTRANSFERASE 15; 1.
DR   PANTHER; PTHR15723:SF0; CARBOHYDRATE SULFOTRANSFERASE 15; 1.
DR   Pfam; PF00685; Sulfotransfer_1; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW   Transferase {ECO:0000256|RuleBase:RU361155};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        80..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          254..509
FT                   /note="Sulfotransferase"
FT                   /evidence="ECO:0000259|Pfam:PF00685"
FT   REGION          119..139
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   561 AA;  64892 MW;  B0CD51B62ED40651 CRC64;
     MRHCINCCIQ LLPDGAHKHQ VNCRGGPHHG HQACPTCKGE NKILFRVDSK QMNLLAVLEV
     RTEGNENWGG FMRFTKGKRC SLVFGLIIMT LVMASYILSG AHQELLISSP FHYGGFPSNP
     SLMDSENPSD TKEHHHQSSV NNISYVKDYP SIKLIINSIT ARIEFTTRQL PDLEDLKKQE
     LHMFSVIPNK FLPNSKSPCW YEEFSGRNTT DPYLTNSYVL YSKRFRSTFD ALRKAFWGHL
     AHAHGKHFRL RCLPHFYIIG QPKCGTTDLY DRLRLHPEVK FSAIKEPHWW TRKRFGIVRL
     RDGLRDRYPV EDYLDLFDLA AHQIHQGLQA SSAKEQSKMN TIIIGEASAS TMWDNNAWTF
     FYDNSTDGEP PFLTQDFIHA FQPNAKLIVM LRDPVERLYS DYLYFASSNK SADDFHEKVT
     EALQLFENCM LDYSLRACVY NNTLNNAMPV RLQVGLYAVY LLDWLSVFDK QQFLILRLED
     HASNVKYTMH KVFQFLNLGP LSEKQEALMT KSPASNARRP EDRNLGPMWP ITQKILRDFY
     RPFNARLAQV LADEAFAWKT T
//