ID   A0A2K5ZAX2_MANLE        Unreviewed;       320 AA.
AC   A0A2K5ZAX2;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=Zinc finger Ran-binding domain-containing protein 2 {ECO:0000256|ARBA:ARBA00017543, ECO:0000256|PIRNR:PIRNR037956};
GN   Name=ZRANB2 {ECO:0000313|Ensembl:ENSMLEP00000024961.1};
OS   Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Mandrillus.
OX   NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000024961.1, ECO:0000313|Proteomes:UP000233140};
RN   [1] {ECO:0000313|Ensembl:ENSMLEP00000024961.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Splice factor required for alternative splicing of
CC       TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice
CC       site selection. {ECO:0000256|ARBA:ARBA00024928}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PIRNR:PIRNR037956}.
CC   -!- SIMILARITY: Belongs to the ZRANB2 family.
CC       {ECO:0000256|ARBA:ARBA00025731, ECO:0000256|PIRNR:PIRNR037956}.
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DR   RefSeq; XP_011833004.1; XM_011977614.1.
DR   AlphaFoldDB; A0A2K5ZAX2; -.
DR   SMR; A0A2K5ZAX2; -.
DR   Ensembl; ENSMLET00000048488.1; ENSMLEP00000024961.1; ENSMLEG00000036639.1.
DR   GeneID; 105537918; -.
DR   CTD; 9406; -.
DR   GeneTree; ENSGT00730000111078; -.
DR   OrthoDB; 585295at2759; -.
DR   Proteomes; UP000233140; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   Gene3D; 4.10.1060.10; Zinc finger, RanBP2-type; 2.
DR   InterPro; IPR001876; Znf_RanBP2.
DR   InterPro; IPR036443; Znf_RanBP2_sf.
DR   InterPro; IPR017337; ZRANB2.
DR   PANTHER; PTHR12999:SF17; ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2; 1.
DR   PANTHER; PTHR12999; ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 ZRANB2-RELATED; 1.
DR   Pfam; PF00641; zf-RanBP; 2.
DR   PIRSF; PIRSF037956; UCP037956_ZnF_Ran; 1.
DR   SMART; SM00547; ZnF_RBZ; 2.
DR   SUPFAM; SSF90209; Ran binding protein zinc finger-like; 2.
DR   PROSITE; PS01358; ZF_RANBP2_1; 2.
DR   PROSITE; PS50199; ZF_RANBP2_2; 2.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|PIRNR:PIRNR037956}; Nucleus {ECO:0000256|PIRNR:PIRNR037956};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   RNA-binding {ECO:0000256|PIRNR:PIRNR037956};
KW   Zinc {ECO:0000256|PIRNR:PIRNR037956};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00322}.
FT   DOMAIN          9..40
FT                   /note="RanBP2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50199"
FT   DOMAIN          65..94
FT                   /note="RanBP2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50199"
FT   REGION          117..320
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        117..132
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        151..180
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        181..198
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        211..242
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   320 AA;  36318 MW;  15F1DFB7CD6CF611 CRC64;
     MSTKNFRVSD GDWICPDKKC GNVNFARRTS CNRCGREKTT EAKMMKAGGT EIGKTLAEKS
     RGLFSANDWQ CKTCSNVNWA RRSECNMCNT PKYAKLEERT GYGGGFNERE NVEYIEREES
     DGEYDEFGRK KKKYRGKAVG PASILKEVED KESEGEEEDE DEDLSKYKLD EDEDEDDADL
     SKYNLDASEE EDSNKKKSNR RSRSKSRSSH SRSSSRSSSP SSSRSRSRSR SRSSSSSQSR
     SRSSSRERSR SRGSKSRSSS RSHRGSSSPR KRSYSSSSSS PERNRKRSRS RSSSSGDRKK
     RRTRSRSPES QVIGENTKQP
//