ID A0A2K5ZDS2_MANLE Unreviewed; 831 AA.
AC A0A2K5ZDS2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Zinc finger protein 780B {ECO:0000313|Ensembl:ENSMLEP00000025972.1};
GN Name=ZNF780B {ECO:0000313|Ensembl:ENSMLEP00000025972.1};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000025972.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000025972.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR RefSeq; XP_011839310.1; XM_011983920.1.
DR RefSeq; XP_011839316.1; XM_011983926.1.
DR AlphaFoldDB; A0A2K5ZDS2; -.
DR Ensembl; ENSMLET00000049506.1; ENSMLEP00000025972.1; ENSMLEG00000037185.1.
DR GeneID; 105542377; -.
DR KEGG; mleu:105542377; -.
DR CTD; 163131; -.
DR GeneTree; ENSGT00940000164600; -.
DR OMA; AFRHQYQ; -.
DR OrthoDB; 5245464at2759; -.
DR Proteomes; UP000233140; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 23.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24399:SF69; FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED; 1.
DR PANTHER; PTHR24399; ZINC FINGER AND BTB DOMAIN-CONTAINING; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 18.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 22.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 12.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 20.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 23.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 6..77
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 163..190
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 191..218
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 219..246
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 247..274
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 275..302
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 303..330
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 331..358
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 359..386
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 387..414
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 415..442
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 443..470
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 471..498
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 499..526
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 527..554
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 555..582
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 583..610
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 611..638
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 639..666
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 667..694
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 695..722
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 723..750
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 751..778
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 779..806
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 831 AA; 96533 MW; 34229ED394C862E4 CRC64;
MVHGSVTFRD VAIDFSQEEW ECLQPEQRTL YRDVMLENYS HLISLGSSVS KPDVITLLEQ
EKEPWIVVRK ETSRWYPDLE SKHGPEKISP ENDIFEINLP KHVIKQISKT LGLEAFYFRN
DSEYRSRFEG LQGHQEGYIN QKIISYEEMP TYASLIYNTH KPYECKEYGK HFSRGSNLIQ
HQSIHTGEKT YKCKECGKAF QLHIQLTQHQ KFHTGEKPFE CKECGKAFSL STQLNRHKNI
HTGEKLFECK ECGKSFNRSS NLTQHQSIHA GVKPHQCKEC GKAFNRGSNL IQHQKIHSNE
KPFVCRECGM TFRYHYQLIE HCRIHTGEKP FECKECRKAF TLLTKLVRHQ KIHIGEKPFE
CRECGKAFSL LNQLNRHKNI HTGEKPFECK ECGKSFNRSS NLIQHQSIHA GVKPYQCKEC
GKGFNRGANL IQHQKIHSNE KPFVCRECEM AFRYHYQLIQ HCQIHTGGKP FECKECGKAF
SLLTQLARHK NIHSGEKPFE CKDCGKAFNR GSNLVQHQSI HTGEKPYECK ECGKTFRLHL
QLSQHEKTHT GEKPFECKEC GKFFCRGSNL NQHRSIHTGK KPFECKECGK AFRLHMHLIR
HQKFHTGEKP FECKECGKAF SLHTQLNRHK NIHTGEKPFE CKECGKSFNR VSNLVQHQSI
HAGVKPYECK ECGKVFNRGS NLIQHQKIHS SEKPFVCKEC RKTFRYHYQL IEHYQIHTGE
KPFECKECGK AFSLLTQLAG HQIIHTGEKP FKCKECGKAF NHGSNLVQPR SVYNGEKPYE
CKECGKAFRL HLQLSLHQKL VQVRNPLNVR NVGQPSDISS NLLNIRKFIL G
//
