ID   A0A2K5ZGW9_MANLE        Unreviewed;       228 AA.
AC   A0A2K5ZGW9;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=Interleukin-33 {ECO:0000256|ARBA:ARBA00016804};
GN   Name=IL33 {ECO:0000313|Ensembl:ENSMLEP00000027038.1};
OS   Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Mandrillus.
OX   NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000027038.1, ECO:0000313|Proteomes:UP000233140};
RN   [1] {ECO:0000313|Ensembl:ENSMLEP00000027038.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle
CC       {ECO:0000256|ARBA:ARBA00004398}. Nucleus
CC       {ECO:0000256|ARBA:ARBA00004123}. Secreted
CC       {ECO:0000256|ARBA:ARBA00004613}. Vesicle
CC       {ECO:0000256|ARBA:ARBA00004373}.
CC   -!- SIMILARITY: Belongs to the IL-1 family. Highly divergent.
CC       {ECO:0000256|ARBA:ARBA00007933}.
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DR   RefSeq; XP_011825271.1; XM_011969881.1.
DR   AlphaFoldDB; A0A2K5ZGW9; -.
DR   Ensembl; ENSMLET00000050581.1; ENSMLEP00000027038.1; ENSMLEG00000037699.1.
DR   GeneID; 105531878; -.
DR   CTD; 90865; -.
DR   GeneTree; ENSGT00390000005185; -.
DR   OrthoDB; 4642349at2759; -.
DR   Proteomes; UP000233140; Unplaced.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005125; F:cytokine activity; IEA:InterPro.
DR   Gene3D; 2.80.10.50; -; 1.
DR   InterPro; IPR026145; IL-33.
DR   PANTHER; PTHR21114; DVS27 PROTEIN; 1.
DR   PANTHER; PTHR21114:SF0; INTERLEUKIN-33; 1.
DR   Pfam; PF15095; IL33; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163}.
SQ   SEQUENCE   228 AA;  25599 MW;  FE442656BAC82049 CRC64;
     MKPKMKYSTN KISTAKRKNT ASKALCFKLG KSQQKAKEVC HVYFTKLRSG LTIKKEACYF
     RRETTKRPSL KTGGKHKGHL VLAACPQQST VECFAFGISG VPNYTRALHD SSITDKVLLS
     YYESQHPSSE SGDGVDGKML MVTLSPTKDC WLQANNKEHS VELHKCEKPL PDQAFFVLHN
     ESFNCVSFEC KTDPGVFIGV KDNHLALIKV DYSENLGREN ILFKLSEI
//