ID A0A2K5ZNT7_MANLE Unreviewed; 254 AA.
AC A0A2K5ZNT7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=TNF receptor superfamily member 9 {ECO:0000313|Ensembl:ENSMLEP00000029428.1};
GN Name=TNFRSF9 {ECO:0000313|Ensembl:ENSMLEP00000029428.1};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000029428.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000029428.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
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DR RefSeq; XP_011836814.1; XM_011981424.1.
DR AlphaFoldDB; A0A2K5ZNT7; -.
DR STRING; 9568.ENSMLEP00000029428; -.
DR Ensembl; ENSMLET00000052984.1; ENSMLEP00000029428.1; ENSMLEG00000038910.1.
DR GeneID; 105540720; -.
DR KEGG; mleu:105540720; -.
DR CTD; 3604; -.
DR GeneTree; ENSGT00730000111279; -.
DR OMA; YLFKQPF; -.
DR OrthoDB; 5471029at2759; -.
DR Proteomes; UP000233140; Unplaced.
DR GO; GO:0009897; C:external side of plasma membrane; IEA:InterPro.
DR GO; GO:0038023; F:signaling receptor activity; IEA:Ensembl.
DR GO; GO:0006915; P:apoptotic process; IEA:InterPro.
DR GO; GO:0008285; P:negative regulation of cell population proliferation; IEA:InterPro.
DR GO; GO:0033084; P:regulation of immature T cell proliferation in thymus; IEA:Ensembl.
DR CDD; cd13410; TNFRSF9; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 2.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR InterPro; IPR020413; TNFR_9.
DR InterPro; IPR034020; TNFRSF9_N.
DR PANTHER; PTHR47139; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9; 1.
DR PANTHER; PTHR47139:SF1; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9; 1.
DR Pfam; PF00020; TNFR_c6; 1.
DR PRINTS; PR01924; TNFACTORR9.
DR SMART; SM00208; TNFR; 2.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS50050; TNFR_NGFR_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00206};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..254
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014432202"
FT TRANSMEM 187..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 47..86
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 47..86
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT DISULFID 65..78
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 68..86
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
SQ SEQUENCE 254 AA; 27849 MW; 5CA626338E8C3890 CRC64;
MGNSCYNIVA TLLLVLNFER TRSLQDLCSN CPAGTFCDNN RSQICSPCPP NSFSSAGGQR
TCDICRQCKG VFKTKKECSS TSNAECDCIS GYHCLGAECS MCEQDCKQGQ ELTKKGCKDC
CFGTFNDQKR GVCRPWTNCS LDGKSVLVNG TKERDVVCGP SPADLSPAAS SATPPAPARE
PGHSPQIIFF LALTSTVVLF LLFFLVLRFS VVKRSRKKLL YIFKQPFMRP VQTTQEEDGC
SCRFPEEEEG GCEL
//
