ID A0A2K5ZSF1_MANLE Unreviewed; 1077 AA.
AC A0A2K5ZSF1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Protogenin {ECO:0000313|Ensembl:ENSMLEP00000030740.1};
GN Name=PRTG {ECO:0000313|Ensembl:ENSMLEP00000030740.1};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000030740.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000030740.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K5ZSF1; -.
DR STRING; 9568.ENSMLEP00000030740; -.
DR Ensembl; ENSMLET00000054305.1; ENSMLEP00000030740.1; ENSMLEG00000039567.1.
DR GeneTree; ENSGT00940000155943; -.
DR OMA; MEDGYQA; -.
DR Proteomes; UP000233140; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0038023; F:signaling receptor activity; IEA:Ensembl.
DR GO; GO:0050768; P:negative regulation of neurogenesis; IEA:Ensembl.
DR CDD; cd00063; FN3; 5.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 9.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170:SF53; BROTHER OF IHOG, ISOFORM G-RELATED; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 5.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 2.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 5.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50853; FN3; 5.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 5..98
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 103..190
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 203..290
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 295..379
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 389..483
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 485..581
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 586..685
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 692..785
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 790..885
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 885..934
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1013..1077
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 889..903
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 904..930
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1013..1028
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1042..1062
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1063..1077
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1077 AA; 118982 MW; 0665070023069A4A CRC64;
VWCFSELSFV KEPQDVTVTR KDPVVLDCQA HGEVPIKVTW LKNGAKVSEN KRIEVLSNGS
LYISEVEGRR GEQSDEGFYQ CLAVNKYGAI LSQKAHLALS TISAFEVQPI STEVHEGGVA
RFACKISSNP PAVITWEFNR TVLPITVDRI TALPTGVLQI YDVSQRDSGN YRCVAATVAH
RRKSMEASLT VIPAKESKSF HTPTIIAGPQ NITASLHQTV VLECMAIGNP KPIISWSRLD
HKSIDVFNTR VLGNGNLMIS DVRLQHAGVY VCRATTPGTR NFTVAMATLT VLAPPSFVEW
PESLTRPRAG TARFVCQAEG IPSPKMSWLK NGRKIHSNGR IKMYNSKLVI NQIIPEDDAI
YQCMAENSQG SILSRARLTV VMSEDRPSAP YNVHAETMSS SAILLAWERP LYNSDKVIAY
SVHYMKAEGL NNEEYQVVIG NDTTHYIIDD LEPASNYTFY IVAYMPMGAS QMSDHVTQNT
LEDVPLRPPE ISLTSRSPTD ILISWLPIPA KYRRGQVVLY RLSFRLSTEN SIQVLELPGT
THEYLLEGLK PDSVYLVRIT AATRVGLGES SVWTSHRTPK ATSVKAPKSP ELHLEPLNCT
TISVRWQQDV EDTAAIQGYK LYYKEEGQQE NGPIFLDTKD LLYTLSGLDP RRKYHVRLLA
YNNVEDGYQA DQTVSTPGCV SVRDRMVPPP PPPHHLYAKA NTSSSIFLHW RRPAFTTAQT
INYTIRCNPV GLQNASLVLY LQTSETHMLV QGLEPNTKYE FAVRLHVDQL SSPWSPVVYH
STLPEAPAGP PVGVKVTLIE DDTALVSWKP PDGPETVVTR YTILYASRKA WIAGEWQVLH
REGAITMALL ENLVAGNVYI VKISASNEVG EGPFSNSVEL AVLPKETSES NQRPKRLDSA
DAKKSSASKT AQNGTQQLPR TSTSLASGNE VGKNLEGAVG NEESLMPMIM PNNFIDAKGG
TDLIINSYGP IIKNNSKKKW FFFQDSKKIQ VEQPQRRFTP AVCFYQPGTT VLISDEDSPS
SPGQTASFSR PFGVAADAEH SANSEGSHET GDSGRFSHES NDEIHLSSVI STTPPNL
//
