ID   A0A2K5ZSZ6_MANLE        Unreviewed;      1261 AA.
AC   A0A2K5ZSZ6;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=Synaptopodin 2 {ECO:0000313|Ensembl:ENSMLEP00000030922.1};
GN   Name=SYNPO2 {ECO:0000313|Ensembl:ENSMLEP00000030922.1};
OS   Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Mandrillus.
OX   NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000030922.1, ECO:0000313|Proteomes:UP000233140};
RN   [1] {ECO:0000313|Ensembl:ENSMLEP00000030922.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the synaptopodin family.
CC       {ECO:0000256|ARBA:ARBA00038161}.
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DR   RefSeq; XP_011832992.1; XM_011977602.1.
DR   AlphaFoldDB; A0A2K5ZSZ6; -.
DR   STRING; 9568.ENSMLEP00000030922; -.
DR   Ensembl; ENSMLET00000054487.1; ENSMLEP00000030922.1; ENSMLEG00000039633.1.
DR   GeneID; 105537914; -.
DR   KEGG; mleu:105537914; -.
DR   CTD; 171024; -.
DR   GeneTree; ENSGT00950000183054; -.
DR   OMA; DCNYNPH; -.
DR   OrthoDB; 5359012at2759; -.
DR   Proteomes; UP000233140; Unplaced.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0005925; C:focal adhesion; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0001725; C:stress fiber; IEA:Ensembl.
DR   GO; GO:0030018; C:Z disc; IEA:Ensembl.
DR   GO; GO:0051393; F:alpha-actinin binding; IEA:Ensembl.
DR   GO; GO:0031005; F:filamin binding; IEA:Ensembl.
DR   CDD; cd00992; PDZ_signaling; 1.
DR   Gene3D; 2.30.42.10; -; 1.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   PANTHER; PTHR24217; PUTATIVE-RELATED; 1.
DR   PANTHER; PTHR24217:SF9; SYNAPTOPODIN-2; 1.
DR   Pfam; PF00595; PDZ; 1.
DR   SMART; SM00228; PDZ; 1.
DR   SUPFAM; SSF50156; PDZ domain-like; 1.
DR   PROSITE; PS50106; PDZ; 1.
PE   3: Inferred from homology;
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233140}.
FT   DOMAIN          6..88
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   REGION          205..233
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          329..369
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          507..551
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          586..801
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          935..963
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        591..611
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        665..687
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1261 AA;  136180 MW;  52B33D191E880D5C CRC64;
     MGTGDFICIS MTGGAPWGFR LQGGKEQKQP LQVAKIRNQS KASGSGLCEG DEVVSINGNP
     CADLTYPEVI KLMESITDSL QMLIKRPSSG INEALISENE NKNLEHLTHG GHVESTTLQI
     RPATKTQCTQ FFLAPVKTEV PLAENQRSGP DCAGSLKEET GLSYQKAPQM PDSQRGRVTE
     ELILREKIEA EQPGPVVELQ LSLSQERHKG ASGPVVALPG PEKSKSPDPD PNLSHDKIVH
     INSIPTNEKA DPFLRSSKII QISSGRELRV IQESEAGDAR LPRVEVILDC SDRQKTEGCR
     LQAGKGCVDS PVEGGQSEAP PSLVSFAVSS EGTEQGEDPR SEKDHSRPHK HRARHARLRR
     SESLSEKQVK EAKSKCKSIA LLLTDAPNPN SKGVLMFKKR RRRARKYTLV SYGTGELERE
     ADEEEEGDKE DTCEVAFLGA SESEVDEELL SDVDDNTQVV NFDWDSGLVN IEKKLNRGDK
     MEMLPDTTGK GALMFAKRRE RMDQITAQKE EDKVGGTPSR EQGAAQTDGL RTMTSYQRRE
     EESVRTQSSV SKSYIEVSHG LGHVPQQNGF SGASETANIQ RMAPMNRTAK PFPGSVNQSA
     TPFSPTRNMT SPIADFPAPP PYSAVTPPPD AFSRGVSSPI AGPAQPPPWP QAAPWSQPAF
     YDSSERIASR DERISVPAKR TGILQEAKRR STTKPMFTFK EPKVSPNPEL LSLLQNSEGK
     RGTGAGGDSG PEEDYLSLGA EACNFMQSSS AKQKTPPPVA PKPAVKSSSS QPVTPVSPVW
     SPGVAPTQPP AFPTSNPSKG TVVSSIKIAQ PSYPPARPAS SLTVAGPFKG PQAAVASQNY
     TPKPTVSTAA VNAAQPGAVG PSNELPGMSG RGAQLFAKRQ SRMEKYVVDS DTVQAHAARA
     QSPTPSLPAS WKYSSNVRAP PPVAYNPIHS PSYPLAALKS QPSAAQASKP GKKKGKKPLN
     ALDVMKHQPY QLNASLFTFQ PPDAKDGLPQ KSSVKVNSAL AMKQALPPRP VNAASPTNVQ
     ASSVYSVPAY TSPPSFFAEA SSPVSASPVP VGVPTSPKQE SASSSYFVAP RPKFSAKKSG
     VTIQESGRSL SLPGRSVPPT ISASPWVYQP TYSYSSKPTD GLEKANKRPT PWEAAAKSPL
     GLVDDAFRPR NIQESIVANV ISAARRKVLP GPPEDWNERL SYIPQSQKAY MGSCGRQEYN
     VTANNNMSTN SQYGSQLPYA YYRQASRNDS TIMSMETRSD YCLPVADYNY NPHPRGWRRQ
     T
//