ID A0A2K5ZWV2_MANLE Unreviewed; 173 AA.
AC A0A2K5ZWV2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Protein lin-7 homolog C {ECO:0000256|ARBA:ARBA00039649};
GN Name=LIN7C {ECO:0000313|Ensembl:ENSMLEP00000032283.1};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000032283.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000032283.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Basolateral cell membrane
CC {ECO:0000256|ARBA:ARBA00004171}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004171}. Cell junction, tight junction
CC {ECO:0000256|ARBA:ARBA00004435}. Cell membrane
CC {ECO:0000256|ARBA:ARBA00004202}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004202}. Lateral cell membrane
CC {ECO:0000256|ARBA:ARBA00023767}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00023767}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}. Postsynaptic density membrane
CC {ECO:0000256|ARBA:ARBA00034098}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00034098}.
CC -!- SIMILARITY: Belongs to the lin-7 family.
CC {ECO:0000256|ARBA:ARBA00008546}.
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DR RefSeq; XP_011820104.1; XM_011964714.1.
DR AlphaFoldDB; A0A2K5ZWV2; -.
DR SMR; A0A2K5ZWV2; -.
DR Ensembl; ENSMLET00000055860.1; ENSMLEP00000032283.1; ENSMLEG00000040354.1.
DR GeneID; 105528118; -.
DR CTD; 55327; -.
DR GeneTree; ENSGT00940000153222; -.
DR OrthoDB; 4175920at2759; -.
DR Proteomes; UP000233140; Unplaced.
DR GO; GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR GO; GO:0016328; C:lateral plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0098839; C:postsynaptic density membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.10.287.650; L27 domain; 1.
DR InterPro; IPR014775; L27_C.
DR InterPro; IPR004172; L27_dom.
DR InterPro; IPR036892; L27_dom_sf.
DR InterPro; IPR017365; LIN7.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR14063; PROTEIN LIN-7 HOMOLOG; 1.
DR PANTHER; PTHR14063:SF5; PROTEIN LIN-7 HOMOLOG C; 1.
DR Pfam; PF02828; L27; 1.
DR Pfam; PF00595; PDZ; 1.
DR PIRSF; PIRSF038039; Lin-7_homologue; 3.
DR SMART; SM00569; L27; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF101288; L27 domain; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS51022; L27; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Cell junction {ECO:0000256|ARBA:ARBA00022427};
KW Exocytosis {ECO:0000256|ARBA:ARBA00022483};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00023257};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW Synapse {ECO:0000256|ARBA:ARBA00023018};
KW Tight junction {ECO:0000256|ARBA:ARBA00022427};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 10..63
FT /note="L27"
FT /evidence="ECO:0000259|PROSITE:PS51022"
FT DOMAIN 69..151
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
SQ SEQUENCE 173 AA; 19186 MW; C3104AA6A69A56E7 CRC64;
MAALGEPVRL ERDICRAIEL LEKLQRSGEV PPQKLQALQR VLQSEFCNAV REATVAAFAA
SEGHSHPRVV ELPKTEEGLG FNIMGGKEQN SPIYISRIIP GGIADRHGGL KRGDQLLSVN
GVSVEGEHHE KAVELLKAAQ GKVKLVVRYT PKVLEEMESR FEKMRSAKRR QQT
//
