ID A0A2K5ZX08_MANLE Unreviewed; 1861 AA.
AC A0A2K5ZX08;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=TSPO associated protein 1 {ECO:0000313|Ensembl:ENSMLEP00000032329.1};
GN Name=TSPOAP1 {ECO:0000313|Ensembl:ENSMLEP00000032329.1};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000032329.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000032329.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RIMBP family.
CC {ECO:0000256|ARBA:ARBA00010749}.
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DR RefSeq; XP_011834595.1; XM_011979205.1.
DR Ensembl; ENSMLET00000055906.1; ENSMLEP00000032329.1; ENSMLEG00000040379.1.
DR GeneID; 105539089; -.
DR KEGG; mleu:105539089; -.
DR CTD; 9256; -.
DR GeneTree; ENSGT00950000183203; -.
DR OrthoDB; 5403222at2759; -.
DR Proteomes; UP000233140; Unplaced.
DR CDD; cd00063; FN3; 1.
DR CDD; cd12014; SH3_RIM-BP_1; 1.
DR CDD; cd12012; SH3_RIM-BP_2; 1.
DR CDD; cd12013; SH3_RIM-BP_3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR035753; RIM-BP_SH3_2.
DR InterPro; IPR035755; RIM-BP_SH3_3.
DR InterPro; IPR040325; RIMBP1/2/3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14234:SF20; PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR-ASSOCIATED PROTEIN 1; 1.
DR PANTHER; PTHR14234; RIM BINDING PROTEIN-RELATED; 1.
DR Pfam; PF07653; SH3_2; 2.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00326; SH3; 3.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF50044; SH3-domain; 3.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50002; SH3; 3.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 653..720
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 884..976
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1629..1697
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1768..1835
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 279..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 340..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 561..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 729..787
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1083..1315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1332..1483
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1505..1614
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1727..1761
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1827..1861
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 123..193
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 417..521
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 288..305
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 600..623
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 739..766
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1112..1128
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1157..1178
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1205..1219
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1259..1279
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1283..1300
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1415..1431
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1545..1559
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1560..1599
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1846..1861
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1861 AA; 200556 MW; EACCA3E4B2CE5719 CRC64;
MEQLTTLPRP GDPGAMEPWA LPTWQSWTPG RGGEPGDAAP SVADTPPAAL QLPELRSEES
SEPKGARSSG PIGGTDPEEA EACLPSLGQQ ASSSGPACQR PEDEEVEAFP KAKLNMGFGD
RPNLELLRAL GELRQRCAIL KEENQMLRKS SFPETEEKVR RLKRKNAELA VIAKRLEERA
RKLQETNLRV VSAPLPRPGA SLELCRKALA RQRARDLSET ASALLAKDKQ IAALQRECRE
LQARLTLVGK EGPQWLHVRD FDRLLRESQR EVLRLQRQIA LRNQRETPPR PPSRPPGPAL
PARAEAPAPG APGEATPQED ADNLPVILGE PEKEQRVQQL ESELSKKRKK CESLEQEARK
KQRRCEELEL QLREAQNENA RLVEENSRLS GRVTEKEQVE WENAELRGQL LGVTQERDSA
LRKSQGLQSK LESLEQVLKH MREVAQRRQQ LEVEHEQARL SLREKQEEVR RLQQAQAEAK
KEHEGAVQLL ESTLDSMQAR VRELEEQCRS QTEQFSLLAQ ELQAFRLHPG PLDLLTSALD
CGTLGDRPPP PCCCSTPRPC RGSGPKDLDL PPGSPGRCTP KSSEPAPATL TGVPRRTAKK
AESLSNSSHS ESIHNSPKSC PTPEVDTASE VEELEADSVS LLPATPEGSR GGARIQVFLA
RYSYNPFEGP NENPEAELPL TAGEYIYVYG NMDEDGFFEG ELMDGRRGLV PSNFVERVSD
DDLLTSLPPE LADLSHSSGP ELSFLSVGGG GSSSGGQSSG GQSQPRPEEE NAGDDLSVSP
SPEGLGEPPA VPYPRCLVVL KQLAHSVVLA WEPPPERVEL HGFHICVNGE LRQALGPGAP
PKAVLENLDL RAGPLHISVQ ALTSRGSSDP LRCCLAVGAR AGVVPSQLRV HRLTATSAEI
TWVPGNSNLA HAIYLNGEEC PPASPSTYWA TFCHLRPGTP YQAQVEAQLP PQGPWEPGWE
RLEQRAATLQ FTTLPAGPPD APLDVQIEPG PSPGILIISW LPVTIDAAGT SNGVRVTGYA
IYADGQKIME VASPTAGSVL VELSQLQLLQ VCREVVVRTM SPHGESADSI PAPITPALAP
ASLPARVSCP SPRPSPEARA PLASASPGPG DPSSPLQHPA PLGTQEPPGA PLASPSREMP
KGSHEDPPAP CSQEETGAAV LGTSEERTAS TSTLGEKDPS PAAPSLAKQE AEWTAGEACP
APSSAQGAMA QQAPNTEACQ GGDPESGLRP RAEKEDAAEL GVHLVNSLVD HGRSSDLSDI
QEEEEEEEEE EEEEEEEELG SRTCSFQKQV AGNSIRENGA KSQPDPFCET DSDEEILEQI
LELPLQQFCS KKLFSIPEEE EEEEEDEEKE KPGAGCSSQD PGPPEPALLG LGCDSGQPRR
PGQCPLSPEP SKAGDCLEDM PGLVGGSSRR RGGGSPEKPP SRRRPPDPRE HCSRLLSNNG
PQASGRPGPT RERGGLPVIE GPRTGLEASG RGRLGPSRRC SRGRALEPGL ASCLSPKCLE
ISIEYDSEDE QEAGSGGISI TSSCYPGDGE AWGTATVGRP RGPPKANSGP KPYPPLPAWE
KGEPERRGRS ATGRAKEPLS RATETREARG QDSSGRRGPQ KRGARVPRPS TAELVPVRSP
SEALAYQHLP VRIFVALFDY DPVSMSPNPD AGEEELPFRE GQILKVFGDK DADGFYRGEG
GGRTGYIPCN MVAEVAVDSP AGRQQLLQRG YLSPDILLEG SGNGPFVYST ARTTGPPPKP
RRSKKAESEG PAQPCPGPPK LVPSTELKAP HSMVAAFDYN PQESSPNMDV EAELPFRAGD
VITVFGGMDD DGFYYGELNG QRGLVPSNFL EGPGPEAGGL DREPRTPQAE SQRTRRRRVQ
C
//
