UniProt: A0A2K5ZZC7

Database: UniProt
Entry: A0A2K5ZZC7_MANLE

LinkDB:  A0A2K5ZZC7_MANLE 
Original site:  A0A2K5ZZC7_MANLE

All links

Ontology (3)   
   GO (3)   
Gene (5)   
   KEGG GENES (1)   
   NCBI-Gene (1)   
   ENSEMBL-UP (3)   
Protein sequence (1)   
   RefSeq(pep) (1)   
Protein domain (4)   
   InterPro (3)   
   Pfam (1)   
All databases (13)   

Download RDF

ID   A0A2K5ZZC7_MANLE        Unreviewed;       261 AA.
AC   A0A2K5ZZC7;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   RecName: Full=Voltage-dependent calcium channel gamma-6 subunit {ECO:0000256|RuleBase:RU363085};
GN   Name=CACNG6 {ECO:0000313|Ensembl:ENSMLEP00000033181.1};
OS   Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Mandrillus.
OX   NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000033181.1, ECO:0000313|Proteomes:UP000233140};
RN   [1] {ECO:0000313|Ensembl:ENSMLEP00000033181.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Regulates the activity of L-type calcium channels that
CC       contain CACNA1C as pore-forming subunit.
CC       {ECO:0000256|RuleBase:RU363085}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU363085}; Multi-
CC       pass membrane protein {ECO:0000256|RuleBase:RU363085}.
CC   -!- SIMILARITY: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
CC       {ECO:0000256|ARBA:ARBA00007111, ECO:0000256|RuleBase:RU363085}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_011834910.1; XM_011979520.1.
DR   AlphaFoldDB; A0A2K5ZZC7; -.
DR   STRING; 9568.ENSMLEP00000033181; -.
DR   Ensembl; ENSMLET00000056762.1; ENSMLEP00000033181.1; ENSMLEG00000040771.1.
DR   GeneID; 105539304; -.
DR   KEGG; mleu:105539304; -.
DR   CTD; 59285; -.
DR   GeneTree; ENSGT00390000007786; -.
DR   OMA; PWQRCLP; -.
DR   OrthoDB; 4230292at2759; -.
DR   Proteomes; UP000233140; Unplaced.
DR   GO; GO:1990454; C:L-type voltage-gated calcium channel complex; IEA:Ensembl.
DR   GO; GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005246; F:calcium channel regulator activity; IEA:Ensembl.
DR   Gene3D; 1.20.140.150; -; 1.
DR   InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR   InterPro; IPR008370; VDCC_g6su.
DR   InterPro; IPR008368; VDCC_gsu.
DR   PANTHER; PTHR15025; VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-1 SUBUNIT-RELATED; 1.
DR   PANTHER; PTHR15025:SF6; VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-6 SUBUNIT; 1.
DR   Pfam; PF13903; Claudin_2; 1.
DR   PRINTS; PR01792; VDCCGAMMA.
DR   PRINTS; PR01794; VDCCGAMMA6.
PE   3: Inferred from homology;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|RuleBase:RU363085};
KW   Calcium channel {ECO:0000256|ARBA:ARBA00022673,
KW   ECO:0000256|RuleBase:RU363085};
KW   Calcium transport {ECO:0000256|ARBA:ARBA00022568,
KW   ECO:0000256|RuleBase:RU363085};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|RuleBase:RU363085};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW   ECO:0000256|RuleBase:RU363085}; Membrane {ECO:0000256|RuleBase:RU363085};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW   Transmembrane {ECO:0000256|RuleBase:RU363085};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU363085};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363085};
KW   Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882,
KW   ECO:0000256|RuleBase:RU363085}.
FT   TRANSMEM        42..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363085"
FT   TRANSMEM        138..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363085"
FT   TRANSMEM        170..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363085"
FT   TRANSMEM        220..242
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363085"
SQ   SEQUENCE   261 AA;  28249 MW;  09D23448432D2BD5 CRC64;
     MMMWSNFFLQ EENRRRGAAG RRRAHGQCRS GLTPEREGKV KLALLLAAVG ATLAVLSVGT
     EFWVELNTYK ANGSAVCEAA HLGLWKVCTK RLWQADVPAD RDTCGPAELP GEANCTYFKF
     FTTGENARIF QRTTKKEVNL AAAVIAVLGL VVMALGCLCI IMVLTKGAEF LLRVGAVCFG
     LSGLLLLVSL EVFRHSVRAL LQGVSPEPPP APRLTYEYSW SLGCGVGAGL ILLLGAGCFL
     LLTLPSWPWG SLCPKRGHRA T
//

DBGET integrated database retrieval system