ID A0A2K5ZZR4_MANLE Unreviewed; 86 AA.
AC A0A2K5ZZR4;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=High affinity immunoglobulin epsilon receptor subunit gamma {ECO:0000256|ARBA:ARBA00021544};
DE AltName: Full=Fc receptor gamma-chain {ECO:0000256|ARBA:ARBA00030402};
DE AltName: Full=Fc-epsilon RI-gamma {ECO:0000256|ARBA:ARBA00030112};
DE AltName: Full=IgE Fc receptor subunit gamma {ECO:0000256|ARBA:ARBA00032977};
GN Name=FCER1G {ECO:0000313|Ensembl:ENSMLEP00000033267.1};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000033267.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000033267.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CD3Z/FCER1G family.
CC {ECO:0000256|ARBA:ARBA00007280}.
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DR RefSeq; XP_011831557.1; XM_011976167.1.
DR AlphaFoldDB; A0A2K5ZZR4; -.
DR SMR; A0A2K5ZZR4; -.
DR Ensembl; ENSMLET00000056848.1; ENSMLEP00000033267.1; ENSMLEG00000040815.1.
DR GeneID; 105536720; -.
DR CTD; 2207; -.
DR GeneTree; ENSGT00390000003894; -.
DR OMA; CRLKIQM; -.
DR OrthoDB; 5356852at2759; -.
DR Proteomes; UP000233140; Unplaced.
DR GO; GO:0032998; C:Fc-epsilon receptor I complex; IEA:InterPro.
DR GO; GO:0019863; F:IgE binding; IEA:UniProtKB-KW.
DR GO; GO:0019767; F:IgE receptor activity; IEA:InterPro.
DR GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR InterPro; IPR021663; CD3_zeta/IgE_Fc_rcpt_gamma.
DR InterPro; IPR042340; FCER1G.
DR InterPro; IPR003110; Phos_immunorcpt_sig_ITAM.
DR PANTHER; PTHR16803; HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR GAMMA-SUBUNIT; 1.
DR PANTHER; PTHR16803:SF0; HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT GAMMA; 1.
DR Pfam; PF02189; ITAM; 1.
DR Pfam; PF11628; TCR_zetazeta; 1.
DR SMART; SM00077; ITAM; 1.
DR PROSITE; PS51055; ITAM_1; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW IgE-binding protein {ECO:0000256|ARBA:ARBA00022972};
KW Immunity {ECO:0000256|ARBA:ARBA00022588};
KW Innate immunity {ECO:0000256|ARBA:ARBA00022588};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..86
FT /note="High affinity immunoglobulin epsilon receptor
FT subunit gamma"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014447396"
FT TRANSMEM 26..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 86 AA; 9637 MW; 445C7536513D7534 CRC64;
MIPAVVLLLL LLVEQAAALG EPQLCYILDA ILFLYGIVLT LLYCRLKIQV RKAAIASYEK
SDGVYTGLST RNQETYETLK HEKPPQ
//
